Antiseizure medications for adults with epilepsy: a review

AM Kanner, MM Bicchi - Jama, 2022 - jamanetwork.com
Importance Epilepsy affects approximately 65 million people worldwide. Persistent seizures
are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) …

Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy

T Tomson, D Battino, R Bromley, S Kochen… - Epileptic …, 2019 - shs.cairn.info
Management of epilepsy in pregnancy: a report from the International League Against Epilepsy
Task Force on Women and Pregnancy | Cairn.info Cairn.info, Matières à réflexion Cairn.info …

Association of prenatal exposure to antiseizure medication with risk of autism and intellectual disability

MH Bjørk, H Zoega, MK Leinonen, JM Cohen… - JAMA …, 2022 - jamanetwork.com
Importance Women with epilepsy frequently need antiseizure medication (ASM) to prevent
seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to …

Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry

T Tomson, D Battino, E Bonizzoni, J Craig… - The Lancet …, 2018 - thelancet.com
Background Evidence for the comparative teratogenic risk of antiepileptic drugs is
insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the …

[HTML][HTML] Postpartum psychiatric disorders

S Meltzer-Brody, LM Howard, V Bergink… - Nature Reviews …, 2018 - nature.com
Pregnancy is a complex and vulnerable period that presents a number of challenges to
women, including the development of postpartum psychiatric disorders (PPDs). These …

Epilepsy: new advances

SL Moshé, E Perucca, P Ryvlin, T Tomson - The Lancet, 2015 - thelancet.com
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …

Valproic acid and epilepsy: from molecular mechanisms to clinical evidences

M Romoli, P Mazzocchetti, R D'Alonzo… - Current …, 2019 - ingentaconnect.com
After more than a century from its discovery, valproic acid (VPA) still represents one of the
most efficient antiepileptic drugs (AEDs). Pre and post-synaptic effects of VPA depend on a …

Synaptopathology involved in autism spectrum disorder

S Guang, N Pang, X Deng, L Yang, F He… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period

I Jones, PS Chandra, P Dazzan, LM Howard - The Lancet, 2014 - thelancet.com
The perinatal period is associated with an increased risk of severe mental disorders. We
summarise the evidence regarding the epidemiology, risk factors, and treatment of severe …

Prenatal valproate exposure and risk of autism spectrum disorders and childhood autism

J Christensen, TK Grønborg, MJ Sørensen, D Schendel… - Jama, 2013 - jamanetwork.com
Importance Valproate is used for the treatment of epilepsy and other neuropsychological
disorders and may be the only treatment option for women of childbearing potential …