Advances in the prerequisite and consequence of STING downstream signalosomes
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is an
evolving DNA-sensing mechanism involved in innate immunity and pathogen defense that …
evolving DNA-sensing mechanism involved in innate immunity and pathogen defense that …
Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors
KB Williams, AT Larsson, BJ Keller, KE Chaney… - …, 2024 - pmc.ncbi.nlm.nih.gov
Neurofibromatosis Type 1 (NF1) is a common cancer predisposition syndrome, caused by
heterozygous loss of function mutations in the tumor suppressor gene NF1. Individuals with …
heterozygous loss of function mutations in the tumor suppressor gene NF1. Individuals with …
[HTML][HTML] Mapping integral cell-type-specific interferon-induced gene regulatory networks (GRNs) involved in systemic lupus erythematosus using systems and …
Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder characterized by
the production of autoantibodies, resulting in inflammation and organ damage. Although …
the production of autoantibodies, resulting in inflammation and organ damage. Although …
Precision medicine revolutionizes cancer diagnosis and treatment
C Han, Q Zhan - Medical Review, 2023 - degruyter.com
Nowadays, according to estimates from the World Health Organization (WHO), cancer still
ranks as the top leading cause of death disease worldwide [1]. In case of the rapid growing …
ranks as the top leading cause of death disease worldwide [1]. In case of the rapid growing …
[HTML][HTML] Anticancer effects of Rosmarinus officinalis leaf extract on KB cell lines
VR Pradeep, S Menaka, V Suresh, S Jayaraman - Cureus, 2024 - ncbi.nlm.nih.gov
Background The value and use of medicinal plants, including the widespread cultivation of
Rosmarinus officinalis, have increased rapidly. R. officinalis, a medicinal plant native to the …
Rosmarinus officinalis, have increased rapidly. R. officinalis, a medicinal plant native to the …