The consequences of matrix effects in mass spectrometry analysis are a major issue of
concern to analytical chemists. The identification of any ion suppressing (or enhancing) …

The exposome is the measure of total environmental exposures and has a significant impact
on human health outcomes. Exposomics research typically examines complex biological …

液相色谱-串联质谱技术作为强有力的分析工具已被广泛应用于多个领域,
但其检测中的基质效应对测定结果准确性的影响需引起重视. 本文综述了液相色谱 …

In this study, the relationship between matrix concentration and suppression of electrospray
ionization (matrix effects) was investigated. Ion suppression of pesticides present in …

Over the past decade, the number of known eicosanoids has expanded immensely and we
have now developed an ultra-performance liquid chromatography–electrospray ionization …

A novel strategy to minimize phospholipids-based matrix effects in bioanalytical LC–MS/MS
assays was evaluated. The phospholipids-based matrix effect was investigated with a …

This study systematically compares matrix effects in liquid chromatography (LC) coupled by
electrospray ionization (ESI) in the positive mode with tandem mass spectrometry (MS/MS) …

The analysis of proteins in biological samples is highly desirable, given their connection to
myriad biological functions and disease states, as well as the growing interest in the …

Biological matrix effects are a source of significant errors in both electrospray (ESI) and
atmospheric pressure chemical ionization (APCI) LC/MS. Glycerophosphocholines …

Matrix effect profiles can be used to visualize the effect of the sample matrix to the data
signals occurring in a chromatogram. In the present study these profiles were generated by …