Intercommunication between cancer cells and with their surrounding and distant
environments is key to the survival, progression and metastasis of the tumour. Exosomes …

Neoplastic cells use various intercellular communication mechanisms in order to adapt to
the local microenvironment, manipulate the immune system, and facilitate metastasis …

With the dramatic development of single-cell RNA sequencing (scRNA-seq) technologies,
the systematic decoding of cell-cell communication has received great research interest. To …

Abstract TP53 mutants (mutp53) are involved in the pathogenesis of most human cancers.
Specific mutp53 proteins gain oncogenic functions (GOFs) distinct from the tumor …

Glioblastoma‐associated macrophages (GAMs) play a crucial role in the progression and
invasiveness of glioblastoma multiforme (GBM); however, the exact crosstalk between GAMs …

Cells sense and respond to the external environment, mainly through proteins presented on
the membrane where their expression and conformation are dynamically regulated via …

Rationale: Synergic reprogramming of metabolic dominates neuroblastoma (NB)
progression. It is of great clinical implications to develop an individualized risk …

Exosomes are small extracellular vesicles with a significant role in most processes
associated with cancer. On one hand, exosomes role in the different hallmarks of cancer has …

Rationale: Estrogen-dependent cancers (eg, breast, endometrial, and ovarian cancers) are
among the leading causes of morbidity and mortality in women worldwide. Recently …

Cancer‐associated fibroblasts (CAFs) play crucial roles in tumor progression, given the
dependence of cancer cells on stromal support. Therefore, understanding how CAFs …