[HTML][HTML] SARS-CoV-2 vaccines in development

F Krammer - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late
2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) …

Humoral responses and serological assays in SARS-CoV-2 infections

Y Galipeau, M Greig, G Liu, M Driedger… - Frontiers in …, 2020 - frontiersin.org
In December 2019, the novel betacoronavirus Severe Acute Respiratory Disease
Coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China. SARS-CoV-2 has since …

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

AK Wheatley, JA Juno, JJ Wang, KJ Selva… - Nature …, 2021 - nature.com
The durability of infection-induced SARS-CoV-2 immunity has major implications for
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …

[HTML][HTML] Functional SARS-CoV-2-specific immune memory persists after mild COVID-19

LB Rodda, J Netland, L Shehata, KB Pruner… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is causing a
global pandemic, and cases continue to rise. Most infected individuals experience mildly …

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

J Seow, C Graham, B Merrick, S Acors, S Pickering… - Nature …, 2020 - nature.com
Antibody responses to SARS-CoV-2 can be detected in most infected individuals 10–15 d
after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS …

[HTML][HTML] Orthogonal SARS-CoV-2 serological assays enable surveillance of low-prevalence communities and reveal durable humoral immunity

TJ Ripperger, JL Uhrlaub, M Watanabe, R Wong… - Immunity, 2020 - cell.com
We conducted a serological study to define correlates of immunity against SARS-CoV-2.
Compared to those with mild coronavirus disease 2019 (COVID-19) cases, individuals with …

[HTML][HTML] A simple protein-based surrogate neutralization assay for SARS-CoV-2

KT Abe, Z Li, R Samson, P Samavarchi-Tehrani… - JCI insight, 2020 - ncbi.nlm.nih.gov
Most of the patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) mount a humoral immune response to the virus within a few weeks of infection, but …

[HTML][HTML] Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity

HM Mengist, AJK Kombe, D Mekonnen, A Abebaw… - Seminars in …, 2021 - Elsevier
Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is
instigating devastating effects on the global health care system whose impacts could be …

Nasal vaccination against SARS-CoV-2: Synergistic or alternative to intramuscular vaccines?

M Tiboni, L Casettari, L Illum - International journal of pharmaceutics, 2021 - Elsevier
It is striking that all marketed SARS-CoV-2 vaccines are developed for intramuscular
administration designed to produce humoral and cell mediated immune responses …

[HTML][HTML] Longitudinal assessment of anti-SARS-CoV-2 antibody dynamics and clinical features following convalescence from a COVID-19 infection

C Gerhards, M Thiaucourt, M Kittel, C Becker… - International Journal of …, 2021 - Elsevier
Introduction The longevity of antibody levels against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and the duration of immunity are current topics of major …