Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

LC Morley, T Tang, E Yasmin… - Cochrane Database …, 2017 - cochranelibrary.com
Background Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …

[HTML][HTML] Role of metformin for ovulation induction in infertile patients with polycystic ovary syndrome (PCOS): a guideline

A Penzias, K Bendikson, S Butts, C Coutifaris… - Fertility and sterility, 2017 - Elsevier
Metformin alone compared with placebo increases the ovulation rate in women with
polycystic ovary syndrome (PCOS) but should not be used as first-line therapy for …

Experts' opinion on inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: A further help for human reproduction and beyond

F Facchinetti, M Appetecchia, C Aragona… - Expert opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: This Experts' opinion provides an updated scientific support to
gynecologists, obstetricians, endocrinologists, nutritionists, neurologists and general …

Use of metformin in polycystic ovary syndrome

R Mathur, CJ Alexander, J Yano, B Trivax… - American journal of …, 2008 - Elsevier
Women with polycystic ovary syndrome (PCOS) have a myriad of phenotypic and clinical
features that may guide therapeutic options for metabolic protection and ovulation induction …

Molecular mechanisms of laparoscopic ovarian drilling and its therapeutic effects in polycystic ovary syndrome

KM Seow, YW Chang, KH Chen, CC Juan… - International Journal of …, 2020 - mdpi.com
Polycystic ovary syndrome (PCOS) is a common endocrinopathy, characterized by chronic
anovulation, hyperandrogenism, and multiple small subcapsular cystic follicles in the ovary …

[HTML][HTML] Effect of preconceptional metformin on abortion risk in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

S Palomba, A Falbo, F Orio Jr, F Zullo - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To evaluate the effect of pregestational metformin administration on abortion
risk in polycystic ovary syndrome (PCOS) patients. DESIGN: Systematic review and meta …

Angiogenesis and antiangiogenic therapy in endometriosis

CM Becker, RJ D'Amato - Microvascular research, 2007 - Elsevier
Endometriosis, the presence of endometrium-like tissue outside of the uterine cavity, is a
common disease among women of reproductive age. Typical symptoms include abdominal …

Drug insight: insulin-sensitizing drugs in the treatment of polycystic ovary syndrome—a reappraisal

A Dunaif - Nature Clinical Practice Endocrinology & Metabolism, 2008 - nature.com
The recognition that insulin resistance has a pivotal role in the pathogenesis of polycystic
ovary syndrome (PCOS) revolutionized our understanding of this complex disorder. PCOS …

The effects of first-line pharmacological treatments for reproductive outcomes in infertile women with PCOS: a systematic review and network meta-analysis

G Peng, Z Yan, Y Liu, J Li, J Ma, N Tong… - Reproductive Biology and …, 2023 - Springer
Background Polycystic ovarian syndrome (PCOS) is one of the most common causes of
infertility in reproductive-age women. However, the efficacy and optimal therapeutic strategy …

Adipose tissue, metabolic syndrome and polycystic ovary syndrome: from pathophysiology to treatment

G Garruti, R Depalo, MG Vita, F Lorusso… - Reproductive …, 2009 - Elsevier
In the last few years, polycystic ovary syndrome (PCOS) has deserved major attention
because it is linked to the same cluster of events that promote the metabolic syndrome. This …