MicroRNAs: roles in cardiovascular development and disease

S Kalayinia, F Arjmand, M Maleki, M Malakootian… - Cardiovascular …, 2021 - Elsevier
Cardiovascular diseases (CVDs) comprise a group of disorders ranging from peripheral
artery, coronary artery, cardiac valve, cardiac muscle, and congenital heart diseases to …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers

KM Akat, DV Moore-McGriff… - Proceedings of the …, 2014 - National Acad Sciences
Heart failure (HF) is associated with high morbidity and mortality and its incidence is
increasing worldwide. MicroRNAs (miRNAs) are potential markers and targets for diagnostic …

Expression profile of MicroRNAs in young stroke patients

KS Tan, A Armugam, S Sepramaniam, KY Lim… - PloS one, 2009 - journals.plos.org
Background The methods currently available for diagnosis and prognosis of cerebral
ischaemia still require further improvements. Micro-RNAs (small non-coding RNAs) have …

MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts

SJ Matkovich, W Wang, Y Tu… - Circulation …, 2010 - Am Heart Assoc
Rationale: MicroRNA (miR)-133a regulates cardiac and skeletal muscle differentiation and
plays an important role in cardiac development. Because miR-133a levels decrease during …

MicroRNAs in idiopathic pulmonary fibrosis

KV Pandit, J Milosevic, N Kaminski - Translational research, 2011 - Elsevier
In this review, we describe the recent advances in the understanding of the role of
microRNAs in idiopathic pulmonary fibrosis (IPF), a chronic progressive and lethal fibrotic …

MicroRNAs miR-1, miR-133a, miR-133b and miR-208 Are Dysregulated in Human Myocardial Infarction

E Boštjančič, N Zidar, D Štajer, D Glavač - Cardiology, 2010 - karger.com
Objectives: MicroRNAs (miRNAs) are noncoding single-stranded RNA molecules that
regulate gene expression in physiological functions, development and disease. In recent …

MicroRNA-221/222 family counteracts myocardial fibrosis in pressure overload–induced heart failure

R Verjans, T Peters, FJ Beaumont, R van Leeuwen… - …, 2018 - Am Heart Assoc
Pressure overload causes cardiac fibroblast activation and transdifferentiation, leading to
increased interstitial fibrosis formation and subsequently myocardial stiffness, diastolic and …

Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization …

Y Ning, P Huang, G Chen, Y Xiong, Z Gong, C Wu, J Xu… - BMC medicine, 2023 - Springer
Abstract Background Extracellular vesicles (EVs) derived from bone marrow mesenchymal
stem cells (MSCs) pretreated with atorvastatin (ATV)(MSCATV-EV) have a superior cardiac …

MicroRNAs expression profiles in cardiovascular diseases

E Bronze-da-Rocha - BioMed research international, 2014 - Wiley Online Library
The current search for new markers of cardiovascular diseases (CVDs) is explained by the
high morbidity and mortality still observed in developed and developing countries due to …