Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Spontaneous subarachnoid haemorrhage

J Claassen, S Park - The Lancet, 2022 - thelancet.com
Subarachnoid haemorrhage (SAH) is the third most common subtype of stroke. Incidence
has decreased over past decades, possibly in part related to lifestyle changes such as …

Management of moderate to severe traumatic brain injury: an update for the intensivist

G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial …

P Toth, S Tarantini, A Csiszar… - American Journal of …, 2017 - journals.physiology.org
Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Early brain injury after poor-grade subarachnoid hemorrhage

V Rass, R Helbok - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review Over the last years, the focus of clinical and animal research in
subarachnoid hemorrhage (SAH) shifted towards the early phase after the bleeding based …

The continuum of spreading depolarizations in acute cortical lesion development: examining Leao's legacy

JA Hartings, CW Shuttleworth… - Journal of Cerebral …, 2017 - journals.sagepub.com
A modern understanding of how cerebral cortical lesions develop after acute brain injury is
based on Aristides Leão's historic discoveries of spreading depression and asphyxial/anoxic …

Full-bandwidth electrophysiology of seizures and epileptiform activity enabled by flexible graphene microtransistor depth neural probes

A Bonaccini Calia, E Masvidal-Codina… - Nature …, 2022 - nature.com
Mapping the entire frequency bandwidth of brain electrophysiological signals is of
paramount importance for understanding physiological and pathological states. The ability …

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

P Klein, R Dingledine, E Aronica, C Bernard… - …, 2018 - Wiley Online Library
The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study

JP Dreier, MKL Winkler, S Major, V Horst, S Lublinsky… - Brain, 2022 - academic.oup.com
Focal brain damage after aneurysmal subarachnoid haemorrhage predominantly results
from intracerebral haemorrhage, and early and delayed cerebral ischaemia. The …

Electroencephalogram in the intensive care unit: a focused look at acute brain injury

A Alkhachroum, B Appavu, S Egawa, B Foreman… - Intensive care …, 2022 - Springer
Over the past decades, electroencephalography (EEG) has become a widely applied and
highly sophisticated brain monitoring tool in a variety of intensive care unit (ICU) settings …