Transposable elements in Drosophila

V Mérel, M Boulesteix, M Fablet, C Vieira - Mobile DNA, 2020 - Springer
Drosophila has been studied as a biological model for many years and many discoveries in
biology rely on this species. Research on transposable elements (TEs) is not an exception …

Genetic redundancy fuels polygenic adaptation in Drosophila

N Barghi, R Tobler, V Nolte, AM Jakšić, F Mallard… - PLoS …, 2019 - journals.plos.org
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …

Insights into mammalian TE diversity through the curation of 248 genome assemblies

AB Osmanski, NS Paulat, J Korstian, JR Grimshaw… - Science, 2023 - science.org
We examined transposable element (TE) content of 248 placental mammal genome
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …

Environmentally-induced transgenerational epigenetic inheritance: implication of PIWI interacting RNAs

K Casier, A Boivin, C Carré, L Teysset - Cells, 2019 - mdpi.com
Environmentally-induced transgenerational epigenetic inheritance is an emerging field. The
understanding of associated epigenetic mechanisms is currently in progress with open …

Annelid comparative genomics and the evolution of massive lineage-specific genome rearrangement in bilaterians

TD Lewin, IJY Liao, YJ Luo - Molecular Biology and Evolution, 2024 - academic.oup.com
The organization of genomes into chromosomes is critical for processes such as genetic
recombination, environmental adaptation, and speciation. All animals with bilateral …

The genomic distribution of transposable elements is driven by spatially variable purifying selection

AM Langmüller, V Nolte, M Dolezal… - Nucleic Acids …, 2023 - academic.oup.com
It is widely accepted that the genomic distribution of transposable elements (TEs) mainly
reflects the outcome of purifying selection and insertion bias. Nevertheless, the relative …

Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary

SP Srivastav, C Feschotte, AG Clark - Genome Research, 2024 - genome.cshlp.org
The piRNA pathway is a highly conserved mechanism to repress transposable element (TE)
activity in the animal germline via a specialized class of small RNAs called piwi-interacting …

Experimentally evolving Drosophila erecta populations may fail to establish an effective piRNA-based host defense against invading P-elements

D Selvaraju, F Wierzbicki, R Kofler - Genome Research, 2024 - genome.cshlp.org
To prevent the spread of transposable elements (TEs), hosts have developed sophisticated
defense mechanisms. In mammals and invertebrates, a major defense mechanism operates …

Reactivation of a somatic errantivirus and germline invasion in Drosophila ovaries

M Yoth, S Maupetit-Méhouas, A Akkouche… - Nature …, 2023 - nature.com
Most Drosophila transposable elements are LTR retrotransposons, some of which belong to
the genus Errantivirus and share structural and functional characteristics with vertebrate …

Dynamics of transposable element invasions with piRNA clusters

R Kofler - Molecular Biology and Evolution, 2019 - academic.oup.com
In mammals and invertebrates, the proliferation of an invading transposable element (TE) is
thought to be stopped by an insertion into a piRNA cluster. Here, we explore the dynamics of …