Chitin, as the main component of the exoskeleton of Arthropoda, is a highly available natural
polymer that can be processed into various value-added products. Its most important …

Despite the many advances that have occurred in the field of vaccine adjuvants, there are
still unmet needs that may enable the development of vaccines suitable for more …

Microneedles (MNs) are micro-scale needles used for drug delivery and other targets. Micro-
scale size endows them with many advantages over hypodermic needles, including …

The dermal route is an attractive route for vaccine delivery due to the easy skin accessibility
and a dense network of immune cells in the skin. The development of microneedles is …

Infectious diseases are a major cause for morbidity and mortality in the older population.
Demographic changes will lead to increasing numbers of older persons over the next …

Most childhood infections occur via the mucosal surfaces, however, parenterally delivered
vaccines are unable to induce protective immunity at these surfaces. In contrast, delivery of …

Dendritic cells (DC) are a heterogeneous family of professional antigen-presenting cells
classically recognized as most potent inducers of adaptive immune responses. In this …

The COVID-19 pandemic is a serious threat to global health and the global economy. The
ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2 …

Mannosylation of Lipid Nanoparticles (LNP) can potentially enhance uptake by Antigen
Presenting Cells, which are highly abundant in dermal tissues, to improve the potency of …

Non-viral gene therapy for hereditary skin diseases is an attractive prospect. However,
research efforts dedicated to this area are rare. Taking advantage of the branched structural …