Organic electrosynthesis is an enabling and sustainable technology, which constitutes a
rapidly expanding field of research. Electrochemical approaches serve as convenient and …

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with
increasing age, being a major component in the development of frailty. Current knowledge …

Aqueous solubility is essential for drug candidates. Poor aqueous solubility is likely to result
in poor absorption, even if the permeation rate is high, since the flux of a drug across the …

Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid
hormones in both women and men. In post-menopausal women, the precipitous depletion of …

Oxidative generation of synthetically important amidyl radicals from N− H amides is an
appealing and yet challenging task. Previous methods require a stoichiometric amount of a …

Sarcopenia is the loss of skeletal muscle mass and function with aging. Although the term
sarcopenia was first coined in 1989, its etiology is still poorly understood. Moreover, a …

A promising strategy to delay and perhaps prevent Alzheimer's disease (AD) is to identify the
age-related changes that put the brain at risk for the disease. A significant normal age …

The androgen receptor (AR) plays a key role in the maintenance of muscle and bone and
the support of male sexual-related functions, as well as in the progression of prostate …

Interest in the development and therapeutic potential of nonsteroidal tissue-selective
androgen receptor modulators (SARMs) a has increased dramatically within the past …

Androgen receptor (AR) plays a critical role in the function of several organs including
primary and accessory sexual organs, skeletal muscle, and bone, making it a desirable …