Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

D Ni, W Bu, EB Ehlerding, W Cai, J Shi - Chemical Society Reviews, 2017 - pubs.rsc.org
Magnetic resonance imaging (MRI) is a highly valuable non-invasive imaging tool owing to
its exquisite soft tissue contrast, high spatial resolution, lack of ionizing radiation, and wide …

Interfacing materials science and biology for drug carrier design

GK Such, Y Yan, APR Johnston… - Advanced …, 2015 - Wiley Online Library
Over the last ten years, there has been considerable research interest in the development of
polymeric carriers for biomedicine. Such delivery systems have the potential to significantly …

Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-associated macrophages toward M1-like phenotype and …

M Song, T Liu, C Shi, X Zhang, X Chen - ACS nano, 2016 - ACS Publications
Hypoxia promotes not only the invasiveness of tumor cells, but also chemoresistance in
cancer. Tumor associated macrophages (TAMs) residing at the site of hypoxic region of …

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

Z Zhao, H Fan, G Zhou, H Bai, H Liang… - Journal of the …, 2014 - ACS Publications
A novel dual-activatable fluorescence/MRI bimodal platform is designed for tumor cell
imaging by using a redoxable manganese dioxide (MnO2) nanosheet–aptamer nanoprobe …

Engineering intracellular delivery nanocarriers and nanoreactors from oxidation-responsive polymersomes via synchronized bilayer cross-linking and permeabilizing …

Z Deng, Y Qian, Y Yu, G Liu, J Hu… - Journal of the …, 2016 - ACS Publications
Reactive oxygen species (ROS) and oxidative stress are implicated in various physiological
and pathological processes, and this feature provides a vital biochemical basis for designing …

Dynamically reversible iron oxide nanoparticle assemblies for targeted amplification of T1-weighted magnetic resonance imaging of tumors

F Li, Z Liang, J Liu, J Sun, X Hu, M Zhao, J Liu, R Bai… - Nano …, 2019 - ACS Publications
Smart magnetic resonance (MR) contrast agents, by which MR contrast can be selectively
enhanced under acidic tumor microenvironment, are anticipated to significantly improve the …

Engineered gadolinium-doped carbon dots for magnetic resonance imaging-guided radiotherapy of tumors

F Du, L Zhang, L Zhang, M Zhang, A Gong, Y Tan… - Biomaterials, 2017 - Elsevier
The effectiveness of radiotherapy can decrease due to inaccurate positioning of machinery
and inherent radioresistance of tumors. To address this issue, we present a novel …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Large‐scale synthesis and medical applications of uniform‐sized metal oxide nanoparticles

HJ Kwon, K Shin, M Soh, H Chang, J Kim… - Advanced …, 2018 - Wiley Online Library
Thanks to recent advances in the synthesis of high‐quality inorganic nanoparticles, more
and more types of nanoparticles are becoming available for medical applications …

Peptide-based nanoprobes for molecular imaging and disease diagnostics

P Zhang, Y Cui, CF Anderson, C Zhang, Y Li… - Chemical Society …, 2018 - pubs.rsc.org
Pathological changes in a diseased site are often accompanied by abnormal activities of
various biomolecules in and around the involved cells. Identifying the location and …