[HTML][HTML] Broad targeting of resistance to apoptosis in cancer

RM Mohammad, I Muqbil, L Lowe, C Yedjou… - Seminars in cancer …, 2015 - Elsevier
Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms

D Sinha, N Sarkar, J Biswas, A Bishayee - Seminars in cancer biology, 2016 - Elsevier
Globally, breast cancer is the most frequently diagnosed cancer among women. The major
unresolved problems with metastatic breast cancer is recurrence after receiving objective …

[HTML][HTML] Endoplasmic reticulum stress and unfolded protein response in breast cancer: the balance between apoptosis and autophagy and its role in drug resistance

L Sisinni, M Pietrafesa, S Lepore, F Maddalena… - International journal of …, 2019 - mdpi.com
The unfolded protein response (UPR) is a stress response activated by the accumulation of
unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER) and its …

[HTML][HTML] Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action

M Behroozaghdam, M Dehghani, A Zabolian… - Cellular and Molecular …, 2022 - Springer
Breast cancer (BC) is one of the most common cancers in females and is responsible for the
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …

[HTML][HTML] Resveratrol, curcumin, paclitaxel and miRNAs mediated regulation of PI3K/Akt/mTOR pathway: go four better to treat bladder cancer

K Khan, C Quispe, Z Javed, MJ Iqbal, H Sadia… - Cancer Cell …, 2020 - Springer
Bladder cancer (BC) is a leading cause of death among urothelial malignancies that more
commonly affect male population. Poor prognosis and resistance to chemotherapy are the …

[HTML][HTML] Flavonoids: New frontier for immuno-regulation and breast cancer control

M Sudhakaran, S Sardesai, AI Doseff - Antioxidants, 2019 - mdpi.com
Breast cancer (BC) remains the second most common cause of cancer-related deaths in
women in the US, despite advances in detection and treatment. In addition, breast cancer …

[HTML][HTML] Anti-inflammatory effects of dietary polyphenols through inhibitory activity against metalloproteinases

T Suzuki, T Ohishi, H Tanabe, N Miyoshi, Y Nakamura - Molecules, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are zinc-dependent metalloproteinases that play
important roles in a variety of diseases, including cancer, cardiovascular disease, diabetes …

[HTML][HTML] Unraveling the anticancer effect of curcumin and resveratrol

AR Pavan, GDB Silva, DH Jornada, DE Chiba… - Nutrients, 2016 - mdpi.com
Resveratrol and curcumin are natural products with important therapeutic properties useful
to treat several human diseases, including cancer. In the last years, the number of studies …

[HTML][HTML] Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives

M Younas, C Hano, N Giglioli-Guivarc'h, BH Abbasi - RSC advances, 2018 - pubs.rsc.org
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …

Sensitization of tumor cells to chemotherapy by natural products: A systematic review of preclinical data and molecular mechanisms

RG de Oliveira Júnior, AFC Adrielly… - Fitoterapia, 2018 - Elsevier
Purpose Tumor cells are spontaneously or adaptively resistant to chemotherapeutic drugs,
eventually leading to the selection of multiresistant cells responsible for tumor growth and …