Microbubble formulations: synthesis, stability, modeling and biomedical applications

A Upadhyay, SV Dalvi - Ultrasound in medicine & biology, 2019 - Elsevier
Microbubbles are increasingly being used in biomedical applications such as ultrasonic
imaging and targeted drug delivery. Microbubbles typically range from 0.1 to 10 µm in size …

Lipid monolayer collapse and microbubble stability

JJ Kwan, MA Borden - Advances in colloid and interface science, 2012 - Elsevier
Microbubbles are micrometer-size gaseous particles suspended in water, and they are often
stabilized by a lipid monolayer shell. Natural microbubbles are found in freshwater and …

Physics of bubble oscillations

W Lauterborn, T Kurz - Reports on progress in physics, 2010 - iopscience.iop.org
Bubbles in liquids, soft and squeezy objects made of gas and vapour, yet so strong as to
destroy any material and so mysterious as at times turning into tiny light bulbs, are the topic …

Growth and dissolution of an encapsulated contrast microbubble: effects of encapsulation permeability

K Sarkar, A Katiyar, P Jain - Ultrasound in medicine & biology, 2009 - Elsevier
Gas diffusion from an encapsulated microbubble is modeled using an explicit linear relation
for gas permeation through the encapsulation. Both the cases of single gas (air) and multiple …

Material characterization of the encapsulation of an ultrasound contrast microbubble and its subharmonic response: Strain-softening interfacial elasticity model

S Paul, A Katiyar, K Sarkar, D Chatterjee… - The Journal of the …, 2010 - pubs.aip.org
Two nonlinear interfacial elasticity models—interfacial elasticity decreasing linearly and
exponentially with area fraction—are developed for the encapsulation of contrast …

Classification of the major nonlinear regimes of oscillations, oscillation properties, and mechanisms of wave energy dissipation in the nonlinear oscillations of coated …

AJ Sojahrood, H Haghi, R Karshafian, MC Kolios - Physics of Fluids, 2021 - pubs.aip.org
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by
bubbles takes place through thermal damping (Td), radiation damping (Rd), and damping …

Effect of anesthesia carrier gas on in vivo circulation times of ultrasound microbubble contrast agents in rats

L Mullin, R Gessner, J Kwan, M Kaya… - Contrast media & …, 2011 - Wiley Online Library
Purpose: Microbubble contrast agents are currently implemented in a variety of both clinical
and preclinical ultrasound imaging studies. The therapeutic and diagnostic capabilities of …

Excitation threshold for subharmonic generation from contrast microbubbles

A Katiyar, K Sarkar - The Journal of the Acoustical Society of America, 2011 - pubs.aip.org
Six models of contrast microbubbles are investigated to determine the excitation threshold
for subharmonic generation. The models are applied to a commercial contrast agent; its …

Aiming for the heart: targeted delivery of drugs to diseased cardiac tissue

RC Scott, D Crabbe, B Krynska, R Ansari… - Expert opinion on drug …, 2008 - Taylor & Francis
Background: The development of a number of regenerative strategies in recent years for
curing heart disease represents a paradigm shift away from conventional approaches which …

Generation of microbubbles via a tapered capillary

W Lu, EQ Li, P Gao - Physics of Fluids, 2023 - pubs.aip.org
We propose a novel method for efficient production of microbubbles based on a tapered
capillary with an interiorly attached filament. When gas–liquid displacement driven by an …