With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …

To become resistant, cancer cells need to activate and maintain molecular defense
mechanisms that depend on an energy trade-off between resistance and essential functions …

Lipid droplet (LD) accumulation is a now well-recognised hallmark of cancer. However, the
significance of LD accumulation in colorectal cancer (CRC) biology is incompletely …

Lipids, phospholipids and cholesterol in particular, are the predominant components of the
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …

One of the most important metabolic hallmarks of cancer cells is deregulation of lipid
metabolism. In addition, enhancing de novo fatty acid (FA) synthesis, increasing lipid uptake …

Despite an increasing arsenal of anticancer therapies, many patients continue to have poor
outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of …

Prostate cancer is the most commonly diagnosed malignancy among Western men and
accounts for the second leading cause of cancer-related deaths. Prostate cancer tends to …

Lipids, as one of the three primary energy sources, provide energy for all cellular life
activities. Lipids are also known to be involved in the formation of cell membranes and play …

Distinguishing tumor from normal glandular breast tissue is an important step in breast-
conserving surgery. Because this distinction can be challenging in the operative setting, up …