Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012) |
Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In Chemical …
Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In Chemical …
HIV “shock and kill” therapy: In need of revision
The implementation of antiretroviral therapy 23 years ago has rendered HIV infection
clinically manageable. However, the disease remains incurable, since it establishes latent …
clinically manageable. However, the disease remains incurable, since it establishes latent …
HIV-1 transcription and latency: an update
C Van Lint, S Bouchat, A Marcello - Retrovirology, 2013 - Springer
Combination antiretroviral therapy, despite being potent and life-prolonging, is not curative
and does not eradicate HIV-1 infection since interruption of treatment inevitably results in a …
and does not eradicate HIV-1 infection since interruption of treatment inevitably results in a …
Why do Euphorbiaceae tick as medicinal plants?: a review of Euphorbiaceae family and its medicinal features
TJ Mwine, P Van Damme - Journal of medicinal plants research, 2011 - biblio.ugent.be
Euphorbiaceae is among the large flowering plant families consisting of a wide variety of
vegetative forms some of which are plants of great importance. Its classification and …
vegetative forms some of which are plants of great importance. Its classification and …
Synergistic reactivation of latent HIV expression by ingenol-3-angelate, PEP005, targeted NF-kB signaling in combination with JQ1 induced p-TEFb activation
Although anti-retroviral therapy (ART) is highly effective in suppressing HIV replication, it
fails to eradicate the virus from HIV-infected individuals. Stable latent HIV reservoirs are …
fails to eradicate the virus from HIV-infected individuals. Stable latent HIV reservoirs are …
Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs
M Coiras, MR López-Huertas… - Nature Reviews …, 2009 - nature.com
HIV-1 can infect both activated and resting, non-dividing cells, following which the viral
genome can be permanently integrated into a host cell chromosome. Latent HIV-1 reservoirs …
genome can be permanently integrated into a host cell chromosome. Latent HIV-1 reservoirs …
Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner
R Mehla, S Bivalkar-Mehla, R Zhang, I Handy… - PloS one, 2010 - journals.plos.org
HIV's ability to establish long-lived latent infection is mainly due to transcriptional silencing in
resting memory T lymphocytes and other non dividing cells including monocytes. Despite an …
resting memory T lymphocytes and other non dividing cells including monocytes. Despite an …
Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies
L Colin, C Van Lint - Retrovirology, 2009 - Springer
The persistence of HIV-1 latent reservoirs represents a major barrier to virus eradication in
infected patients under HAART since interruption of the treatment inevitably leads to a …
infected patients under HAART since interruption of the treatment inevitably leads to a …
Targeting NF-κB signaling with protein kinase C agonists as an emerging strategy for combating HIV latency
G Jiang, S Dandekar - AIDS research and human retroviruses, 2015 - liebertpub.com
Highly active antiretroviral therapy (HAART) is very effective in suppressing HIV-1 replication
and restoring immune functions in HIV-infected individuals. However, it fails to eradicate the …
and restoring immune functions in HIV-infected individuals. However, it fails to eradicate the …
Targeting HIV latency: pharmacologic strategies toward eradication
S Xing, RF Siliciano - Drug discovery today, 2013 - Elsevier
The latent reservoir for HIV-1 in resting CD4+ T cells remains a major barrier to HIV-1
eradication, even though highly active antiretroviral therapy (HAART) can successfully …
eradication, even though highly active antiretroviral therapy (HAART) can successfully …