[HTML][HTML] Mechanisms of ferroptosis regulating oxidative stress and energy metabolism in myocardial ischemia-reperfusion injury and a novel perspective of natural …

T Zhang, W Deng, Y Deng, Y Liu, S Xiao, Y Luo… - Biomedicine & …, 2023 - Elsevier
Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Thymoquinone: review of its potential in the treatment of neurological diseases

FH Pottoo, AM Ibrahim, A Alammar, R Alsinan, M Aleid… - Pharmaceuticals, 2022 - mdpi.com
Thymoquinone (TQ) possesses anticonvulsant, antianxiety, antidepressant, and
antipsychotic properties. It could be utilized to treat drug misuse or dependence, and those …

Targeting dysregulated intracellular immunometabolism within synovial microenvironment in rheumatoid arthritis with natural products

S Hu, Y Lin, Y Tang, J Zhang, Y He, G Li… - Frontiers in …, 2024 - frontiersin.org
Immunometabolism has been an emerging hotspot in the fields of tumors, obesity, and
atherosclerosis in recent decades, yet few studies have investigated its connection with …

Plant foods and their bioactives as dietary enhancers for colon cancer treatment with 5-fluorouracil

Z Yang, CL Cespedes-Acuña, Z Yang… - Food Reviews …, 2025 - Taylor & Francis
Cancer is the world's second most common cause of death, with colon cancer (CC) ranking
third in prevalence and second in cancer-related fatalities. CC originates in the colon or …

Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review

E Sadeghi, M Imenshahidi, H Hosseinzadeh - Molecular Biology Reports, 2023 - Springer
Background Nigella sativa and its main bioactive ingredient, thymoquinone, exhibit various
pharmacological activities, including neuroprotective, nephroprotective, cardioprotective …

Evaluation of the antimicrobial effects of Capsicum, Nigella sativa, Musa paradisiaca L., and Citrus limetta: A review

SA Bhatti, MH Hussain, MZ Mohsin… - … in Sustainable Food …, 2022 - frontiersin.org
The extensive use of antibiotics and vaccines against microbial infections can result in long-
term negative effects on humans and the environment. However, there are a number of …

Mechanism of the antidiabetic action of Nigella sativa and Thymoquinone: a review

A Shaukat, A Zaidi, H Anwar, N Kizilbash - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction Long used in traditional medicine, Nigella sativa (NS; Ranunculaceae) has
shown significant efficacy as an adjuvant therapy for diabetes mellitus (DM) management by …

Herbal honey preparations of Curcuma xanthorriza and black cumin protect against carcinogenesis through antioxidant and immunomodulatory activities in Sprague …

T Hidayati, I Indrayanti, E Darmawan, A Akrom - Nutrients, 2023 - mdpi.com
Background: Traditionally, Curcuma xanthorriza (CX), black cumin seed (BC), and honey
have been used by the Indonesian people as medicinal ingredients to treat various health …

Morphological, phytochemical, and transcriptome analyses provide insights into the biosynthesis of monoterpenes in Monarda citriodora

P Sharma, MA Wajid, M Fayaz, S Bhat, AK Nautiyal… - Planta, 2023 - Springer
Main conclusion Morphological, phytochemical, and transcriptome analyses revealed
candidate genes involved in the biosynthesis of volatile monoterpenes and development of …

Thymoquinone effect on monocyte-derived macrophages, cell-surface molecule expression, and phagocytosis

NA Alkhattabi, SA Hussein, NI Tarbiah, RY Alzahri… - Nutrients, 2022 - mdpi.com
Macrophages are one of the most important cells in the immune system. They act as links
between innate and adaptive immunities. In this study, the aim was to examine …