Microglia shift toward an inflammatory phenotype during aging that is thought to exacerbate age-related neurodegeneration. The molecular and cellular signals that resolve …
S Roy, MB Sleiman, P Jha, JF Ingels, CJ Chapman… - Nature …, 2021 - nature.com
How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically …
Fungi can serve as highly tractable models for understanding genetic basis of sexual development in multicellular organisms. Applying a reverse-genetic approach to advance …
Fungal model species have contributed to many aspects of modern biology, from biochemistry and cell biology to molecular genetics. Nevertheless, only a few genes …
Understanding the genetic basis of the switch from asexual to sexual lifestyles in response to sometimes rapid environmental changes is one of the major challenges in fungal ecology …
AK Cashion, DK Hathaway, A Stanfill… - Clinical …, 2014 - Wiley Online Library
Clinically useful predictors of weight gain could be used to reduce the epidemic of post‐ kidney transplant obesity and resulting co‐morbidities. The purpose of this study was to …
F Trail, Z Wang, K Stefanko, C Cubba… - PLoS genetics, 2017 - journals.plos.org
Changes in gene expression have been hypothesized to play an important role in the evolution of divergent morphologies. To test this hypothesis in a model system, we …
Objective To apply discovery-based computational methods to nationally representative data from the Centers for Disease Control and Preventions' Youth Risk Behavior …
F Xu, J Gao, S Bergmann, AC Sims… - Frontiers in …, 2021 - frontiersin.org
Acute lung injury (ALI) is an important cause of morbidity and mortality after viral infections, including influenza A virus H1N1, SARS-CoV, MERS-CoV, and SARS-CoV-2. The …