Negative symptoms of schizophrenia: new developments and unanswered research questions

S Galderisi, A Mucci, RW Buchanan… - The Lancet Psychiatry, 2018 - thelancet.com
Negative symptoms of schizophrenia are associated with poor functional outcome and place
a substantial burden on people with this disorder, their families, and health-care systems …

Definition and description of schizophrenia in the DSM-5

R Tandon, W Gaebel, DM Barch, J Bustillo, RE Gur… - Schizophrenia …, 2013 - Elsevier
Although dementia praecox or schizophrenia has been considered a unique disease for
over a century, its definitions and boundaries have changed over this period and its etiology …

EPA guidance on assessment of negative symptoms in schizophrenia

S Galderisi, A Mucci, S Dollfus, M Nordentoft… - European …, 2021 - cambridge.org
BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …

The current conceptualization of negative symptoms in schizophrenia

SR Marder, S Galderisi - World Psychiatry, 2017 - Wiley Online Library
Negative symptoms have long been conceptualized as a core aspect of schizophrenia. They
play a key role in the functional outcome of the disorder, and their management represents a …

[HTML][HTML] Thirty years of research on negative symptoms of schizophrenia: A scientometric analysis of hotspots, bursts, and research trends

M Sabe, C Chen, N Perez, M Solmi, A Mucci… - Neuroscience & …, 2023 - Elsevier
Research on negative symptoms of schizophrenia has received renewed interest since the
1980s. A scientometric analysis that objectively maps scientific knowledge, with changes in …

A meta-analysis of social skills training and related interventions for psychosis

DT Turner, E McGlanaghy, P Cuijpers… - Schizophrenia …, 2018 - academic.oup.com
Objective Evidence suggests that social skills training (SST) is an efficacious intervention for
negative symptoms in psychosis, whereas evidence of efficacy in other psychosis symptom …

The relationship between negative symptoms and depression in schizophrenia: a systematic review

CR Krynicki, R Upthegrove, JFW Deakin… - Acta Psychiatrica …, 2018 - Wiley Online Library
Objective To provide an update on the evidence base for the nature of the relationship
between negative symptoms and depressive features in people with schizophrenia, and …

Secondary negative symptoms—a review of mechanisms, assessment and treatment

M Kirschner, A Aleman, S Kaiser - Schizophrenia research, 2017 - Elsevier
Negative symptoms in schizophrenia may be classified as primary or secondary. Primary
negative symptoms are thought to be intrinsic to schizophrenia, while secondary negative …

Treatment of negative symptoms: where do we stand, and where do we go?

A Aleman, TM Lincoln, R Bruggeman, I Melle… - Schizophrenia …, 2017 - Elsevier
Negative symptoms, eg social withdrawal, reduced initiative, anhedonia and affective
flattening, are notoriously difficult to treat. In this review, we take stock of recent research into …

Motivational and neurocognitive deficits are central to the prediction of longitudinal functional outcome in schizophrenia

G Fervaha, G Foussias, O Agid… - Acta Psychiatrica …, 2014 - Wiley Online Library
Objective Functional impairment is characteristic of most individuals with schizophrenia;
however, the key variables that undermine community functioning are not well understood …