Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos

B Weijts, E Gutierrez, SK Saikin, AJ Ablooglu… - Nature …, 2018 - nature.com
Arteries and veins are formed independently by different types of endothelial cells (ECs). In
vascular remodeling, arteries and veins become connected and some arteries become …

Endothelial struts enable the generation of large lumenized blood vessels de novo

B Weijts, I Shaked, M Ginsberg, D Kleinfeld… - Nature cell …, 2021 - nature.com
De novo blood vessel formation occurs through coalescence of endothelial cells (ECs) into a
cord-like structure, followed by lumenization either through cell-,–or cord-hollowing …

[HTML][HTML] CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development

A Klaus, T Clapes, L Yvernogeau, S Basu, B Weijts… - Cell Reports, 2022 - cell.com
Hematopoietic stem cells (HSCs) express a large variety of cell surface receptors that are
associated with acquisition of self-renewal and multipotent properties. Correct expression of …

A layered mounting method for extended time-lapse confocal microscopy of whole zebrafish embryos

S Upadhyay, L Vergara, P Shah… - Journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Dynamics of development can be followed by confocal time-lapse microscopy of live
transgenic zebrafish embryos expressing fluorescence in specific tissues or cells. A difficulty …

Endothelial struts, a mechanism to generate large lumenized blood vessels de novo

B Weijts, I Shaked, W Li, M Ginsberg, D Kleinfeld… - bioRxiv, 2019 - biorxiv.org
Lumenization of de novo formed blood vessels occurs either through cell hollowing
(intracellular lumen)–or cord hollowing (extracellular lumen)–and restricts thereby the initial …

Blood flow-induced Notch activation and endothelial migration enable embryonic vascular remodeling

B Weijts, E Gutierrez, SK Saikin, AJ Ablooglu, D Traver… - bioRxiv, 2016 - biorxiv.org
Arteries and veins are formed independently by different types of endothelial cells (ECs). In
vascular remodeling, arteries and veins become connected and some arteries become …