CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

It is increasingly accepted that early cognitive impairment in Alzheimer's disease results in
considerable part from synaptic dysfunction caused by the accumulation of a range of …

Growing evidence suggests that synaptic signaling is compromised in the aging brain and in
Alzheimer's disease (AD), contributing to synaptic decline. Wnt signaling is a prominent …

The non-canonical Wnt/Ca2+ signaling cascade is less characterized than their canonical
counterpart, the Wnt/b-catenin pathway. The non-canonical Wnt signaling pathways are …

Alzheimer's disease (AD) is the 3rd most costly disease and the leading cause of dementia.
It can linger for many years, but ultimately is fatal, the 6th leading cause of death …

Synaptic dysfunction is closely related to Alzheimer's disease (AD) which is also recognized
as synaptic disorder. β-amyloid (Aβ) is one of the main pathogenic factors in AD, which …

Wnts comprise a large family of proteins that have shown to be part of a signaling cascade
that regulates several aspects of development including organogenesis, midbrain …

Astrocytes are highly specialized glial cells responsible for trophic and metabolic support of
neurons. They are associated to ionic homeostasis, the regulation of cerebral blood flow and …

The Wnt signaling pathway plays a role in the development of the central nervous system
and growing evidence indicates that Wnts also regulates the structure and function of the …

Ageing increases susceptibility to neurodegenerative disorders, such as Alzheimer's
disease (AD). Serum levels of sclerostin, an osteocyte-derived Wnt–β-catenin signalling …