Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …

As we age, we experience changes in our nighttime sleep and daytime wakefulness.
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …

Neuroinflammation is a central mechanism involved in neurodegeneration as observed in
Alzheimer's disease (AD), the most prevalent form of neurodegenerative disease …

Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …

Emerging findings suggest that compromised cellular bioenergetics and DNA repair
contribute to the pathogenesis of Alzheimer's disease (AD), but their role in disease-defining …

Background Microglia, the brain's principal immune cell, are increasingly implicated in
Alzheimer's disease (AD), but the molecular interfaces through which these cells contribute …

Neurodegenerative diseases are debilitating disorders that feature progressive and
selective loss of function or structure of anatomically or physiologically associated neuronal …

Optical clearing methods facilitate deep biological imaging by mitigating light scattering in
situ. Multi-scale high-resolution imaging requires preservation of tissue integrity for accurate …

Microglia and astrocytes play essential roles in the central nervous system contributing to
many functions including homeostasis, immune response, blood–brain barrier maintenance …

The prevalence of dementia is increasing in our aging population at an alarming rate.
Because of the heterogeneity of clinical presentation and complexity of disease …