Ethnobotany and the role of plant natural products in antibiotic drug discovery

G Porras, F Chassagne, JT Lyles, L Marquez… - Chemical …, 2020 - ACS Publications
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

Natural xanthones and skin inflammatory diseases: Multitargeting mechanisms of action and potential application

NV Gunter, SS Teh, YM Lim, SH Mah - Frontiers in Pharmacology, 2020 - frontiersin.org
The pathogenesis of skin inflammatory diseases such as atopic dermatitis, acne, psoriasis,
and skin cancers generally involve the generation of oxidative stress and chronic …

Nanoparticle drug delivery systems for α-mangostin

N Wathoni, A Rusdin, K Motoyama, IM Joni… - Nanotechnology …, 2020 - Taylor & Francis
Abstract α-Mangostin, a xanthone derivative from the pericarp of Garcinia mangostana L.,
has numerous bioactivities and pharmacological properties. However, α-mangostin has low …

[HTML][HTML] Effects of the antimicrobial glabridin on membrane integrity and stress response activation in Listeria monocytogenes

A Bombelli, C Araya-Cloutier, S Boeren… - Food Research …, 2024 - Elsevier
Glabridin is a prenylated isoflavan which can be extracted from liquorice roots and has
shown antimicrobial activity against foodborne pathogens and spoilage microorganisms …

Nanoformulations of α-mangostin for cancer drug delivery system

L Meylina, M Muchtaridi, IM Joni, AFA Mohammed… - Pharmaceutics, 2021 - mdpi.com
Natural compounds are emerging as effective agents for the treatment of malignant
diseases. The active constituent of α-mangostin from the pericarp of Garcinia mangostana L …

The diverse bioactivity of α-mangostin and its therapeutic implications

T Chavan, A Muth - Future Medicinal Chemistry, 2021 - Taylor & Francis
α-Mangostin is a xanthone natural product isolated as a secondary metabolite from the
mangosteen tree. It has attracted a great deal of attention due to its wide-ranging effects on …

Transcriptomic and proteomic profiling response of methicillin-resistant Staphylococcus aureus (MRSA) to a novel bacteriocin, plantaricin GZ1-27 and its inhibition of …

H Du, L Zhou, Z Lu, X Bie, H Zhao, YD Niu… - Applied Microbiology and …, 2020 - Springer
Methicillin-resistant Staphylococcus aureus (MRSA) has become a worrisome superbug,
due to its wide distribution and multidrug resistance. To characterize effects of a newly …

A review on α-mangostin as a potential multi-target-directed ligand for Alzheimer's disease

A Yang, C Liu, J Wu, X Kou, R Shen - European Journal of Pharmacology, 2021 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by
progressive memory loss, declining language skills and other cognitive disorders. AD has …

Umbelliferone Impedes Biofilm Formation and Virulence of Methicillin-Resistant Staphylococcus epidermidis via Impairment of Initial Attachment and Intercellular …

TK Swetha, M Pooranachithra… - Frontiers in Cellular …, 2019 - frontiersin.org
Staphylococcus epidermidis is an opportunistic human pathogen, which is involved in
numerous nosocomial and implant associated infections. Biofilm formation is one of the …

Antimicrobial activity of α-mangostin against Staphylococcus species from companion animals in vitro and therapeutic potential of α-mangostin in skin diseases …

SY Park, JH Lee, SY Ko, N Kim, SY Kim… - Frontiers in Cellular and …, 2023 - frontiersin.org
Antimicrobial resistance in Staphylococcus species from companion animals is becoming
increasingly prevalent worldwide. S. pseudintermedius is a leading cause of skin infections …