Neuroinflammation, stroke, blood-brain barrier dysfunction, and imaging modalities
E Candelario-Jalil, RM Dijkhuizen, T Magnus - Stroke, 2022 - Am Heart Assoc
Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …
Immune cells in the BBB disruption after acute ischemic stroke: targets for immune therapy?
Y Qiu, C Zhang, A Chen, H Wang, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …
Inflammatory responses after ischemic stroke
JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …
tissue repair. This is a complex process involving a range of cell types and effector …
Neuroimmune mechanisms and therapies mediating post-ischaemic brain injury and repair
T Shichita, H Ooboshi, A Yoshimura - Nature Reviews Neuroscience, 2023 - nature.com
The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …
IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease
Neuroinflammation in patients with Alzheimer's disease (AD) and related mouse models has
been recognized for decades, but the contribution of the recently described meningeal …
been recognized for decades, but the contribution of the recently described meningeal …
T cell response in ischemic stroke: from mechanisms to translational insights
D Zhang, J Ren, Y Luo, Q He, R Zhao, J Chang… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke, caused by a sudden disruption of blood flow to the brain, is a leading cause
of death and exerts a heavy burden on both patients and public health systems. Currently …
of death and exerts a heavy burden on both patients and public health systems. Currently …
Crosstalk between γδ T cells and the microbiota
The role of the microbiota in the development and function of γδ T cells—a T cell subset
characterized by a T cell receptor composed of one γ-chain and one δ-chain—has been …
characterized by a T cell receptor composed of one γ-chain and one δ-chain—has been …
Tissue adaptations of memory and tissue-resident gamma delta T cells
C Khairallah, TH Chu, BS Sheridan - Frontiers in immunology, 2018 - frontiersin.org
Epithelial and mucosal barriers are critical interfaces physically separating the body from the
outside environment and are the tissues most exposed to microorganisms and potential …
outside environment and are the tissues most exposed to microorganisms and potential …
Immune responses in stroke: how the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?
Stroke is one of the leading causes of death and disability worldwide. The long‐standing
dogma that stroke is exclusively a vascular disease has been questioned by extensive …
dogma that stroke is exclusively a vascular disease has been questioned by extensive …
Th17 and cognitive impairment: possible mechanisms of action
T helper 17 (Th17) cells represent a distinct population of immune cells, important in the
defense of the organism against extracellular infectious agents. Because of their cytokine …
defense of the organism against extracellular infectious agents. Because of their cytokine …