Cognitive development prior to onset of psychosis

J Mollon, A Reichenberg - Psychological medicine, 2018 - cambridge.org
Schizophrenia patients commonly exhibit substantial and diffuse cognitive impairment.
Evidence suggests that subtle cognitive deficits are already apparent in childhood and …

A review of molecular genetic studies of neurocognitive deficits in schizophrenia

G Zai, TW Robbins, BJ Sahakian… - … & Biobehavioral Reviews, 2017 - Elsevier
Schizophrenia is a complex and debilitating illness with strong genetic loading. In line with
its heterogeneous symptomatology, evidence suggests genetic etiologies for the …

[HTML][HTML] The COMT (rs165599) gene polymorphism contributes to chemotherapy-induced cognitive impairment in breast cancer patients

H Cheng, W Li, C Gan, B Zhang, Q Jia… - American journal of …, 2016 - ncbi.nlm.nih.gov
The present study aimed to investigate the effect of genetic polymorphisms of catechol-O-
methyl transferase (COMT), apolipoprotein E (APOE), and brain derived neurotrophic factor …

Personalised treatment for cognitive dysfunction in individuals with schizophrenia spectrum disorders

A Medalia, AM Saperstein, MC Hansen… - Neuropsychological …, 2018 - Taylor & Francis
Cognitive deficits are a well-recognised issue for individuals diagnosed with schizophrenia
spectrum disorders. Despite positive group findings for the use of cognitive remediation (CR) …

[HTML][HTML] Self-reported intake of high-fat and high-sugar diet is not associated with cognitive stability and flexibility in healthy men

H Hartmann, LK Janssen, N Herzog, F Morys… - Appetite, 2023 - Elsevier
Animal studies indicate that a high-fat/high-sugar diet (HFS) can change dopamine signal
transmission in the brain, which could promote maladaptive behavior and decision-making …

Factors associated with response and resistance to cognitive remediation in schizophrenia: a critical review

S Barlati, G Deste, A Galluzzo, AP Perin… - Frontiers in …, 2019 - frontiersin.org
Cognitive impairment is a central feature of schizophrenia and has shown to play a crucial
role in the psychosocial function of the disorder. Over the past few years, several cognitive …

Analyzing the genes related to nicotine addiction or schizophrenia via a pathway and network based approach

Y Hu, Z Fang, Y Yang, D Rohlsen-Neal, F Cheng… - Scientific Reports, 2018 - nature.com
The prevalence of tobacco use in people with schizophrenia is much higher than in general
population, which indicates a close relationship between nicotine addiction and …

The interactive effect of genetic polymorphisms of IL-10 and COMT on cognitive function in schizophrenia

J Wang, H Xu, D Wang, G Wei, H Zhou, L Wang… - Journal of Psychiatric …, 2021 - Elsevier
Dopaminergic and inflammatory systems have been proven to play an important role in the
cognitive deficits of schizophrenia. Although increasing evidence indicates two systems …

[HTML][HTML] Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors

Y Ma, J Li, Y Xu, Y Wang, Y Yao, Q Liu, M Wang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The prevalence of smoking is significantly higher in persons with schizophrenia (SCZ) than
in the general population. However, the biological mechanisms of the comorbidity of …

Association between catechol-O-methyltransferase genetic variation and functional connectivity in patients with first-episode schizophrenia

H Wang, B Zhang, B Zeng, Y Tang, T Zhang… - Schizophrenia …, 2018 - Elsevier
Dopamine in the prefrontal cortex (PFC) plays an important role in cognitive performance
and regulates by catechol-O-methyltransferase (COMT) expression. To clarify the effect of …