Breast cancer evolves thanks to a dense and close interaction with the surrounding tumor
microenvironment (TME). Fibroblasts, leukocytes, blood and lymphatic endothelial cells and …

Ovarian cancer remains a deadly diagnosis with an 85% recurrence rate and a 5-year
survival rate of only 46%. The poor outlook of this disease has improved little over the past …

Breast cancer is characterized by high aggression, poor prognosis, and high recurrence
rate. Early detection and specific targeted treatment with less toxicity are the ultimate goals …

Transforming growth factor β1 (TGF-β1), a cytokine whose levels are elevated in the airways
of patients with asthma, perpetuates airway inflammation and modulates airway structural …

A desirable cancer therapeutic strategy is supposed to have effective ability to not only exert
maximum anticancer ability but also inspire antitumor immunity for preventing tumor relapse …

Breast cancer (BC) metastasis is an enormous challenge targeting BC therapy. The
extracellular matrix (ECM), the principal component of the BC metastasis niche, is the pivotal …

An increase of cellular phosphocholine (PC) and total choline (tCho)-containing compounds
as well as alterations in lipids have been consistently observed in cancer cells and tissue …

Senescence is recognized as a cellular state acquired in response to various stresses. It
occurs in correlation with the activation of the Unfolded Protein Response (UPR) pathway …

Multifunctional nanocomposites that possess imaging and high-performance therapeutic
features are experiencing a surge in interest in the precision clinical anticancer treatment. In …

Cells continuously sense and react to mechanical cues from their surrounding matrix, which
consists of a fibrous network of biopolymers that influences their fate and behavior. Several …