Effective treatment options for musculoskeletal pain in primary care: a systematic overview of current evidence

OO Babatunde, JL Jordan, DA Van der Windt, JC Hill… - PloS one, 2017 - journals.plos.org
Background & aims Musculoskeletal pain, the most common cause of disability globally, is
most frequently managed in primary care. People with musculoskeletal pain in different body …

[HTML][HTML] Management of neck pain and associated disorders: a clinical practice guideline from the Ontario Protocol for Traffic Injury Management (OPTIMa) …

P Côté, JJ Wong, D Sutton, HM Shearer, S Mior… - European Spine …, 2016 - Springer
Purpose To develop an evidence-based guideline for the management of grades I–III neck
pain and associated disorders (NAD). Methods This guideline is based on recent systematic …

Botulinum toxins: mechanisms of action, antinociception and clinical applications

A Wheeler, HS Smith - Toxicology, 2013 - Elsevier
Botulinum toxin (BoNT) is a potent neurotoxin that is produced by the gram-positive, spore-
forming, anaerobic bacterium, Clostridum botulinum. There are 7 known immunologically …

An evidence-based review of botulinum toxin (Botox) applications in non-cosmetic head and neck conditions

R Persaud, G Garas, S Silva… - JRSM short …, 2013 - journals.sagepub.com
Botulinum toxin (Botox) is an exotoxin produced from Clostridium botulinum. It works by
blocking the release of acetylcholine from the cholinergic nerve end plates leading to …

Botulinum toxin A, brain and pain

I Matak, Z Lacković - Progress in neurobiology, 2014 - Elsevier
Botulinum neurotoxin type A (BoNT/A) is one of the most potent toxins known and a potential
biological threat. At the same time, it is among the most widely used therapeutic proteins …

Neck pain: initial evaluation and management

MA Childress, SJ Stuek - American Family Physician, 2020 - aafp.org
Neck pain is a common presenting symptom in the primary care setting and causes
significant disability. The broad differential diagnosis requires an efficient but global …

[HTML][HTML] Occipital neuralgia and cervicogenic headache: diagnosis and management

R Barmherzig, W Kingston - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review Occipital neuralgia (ON) and cervicogenic headache (CGH) are
secondary headache disorders with occipital pain as a key feature. Due to significant …

Botulinum toxin for myofascial pain syndromes in adults

A Soares, RB Andriolo, AN Atallah… - Cochrane Database …, 2012 - cochranelibrary.com
Background Myofascial pain syndrome (MPS) is a regional muscular pain syndrome
characterised by the presence of trigger points, which are painful points in one or more …

[HTML][HTML] The therapeutic usage of botulinum toxin (Botox) in non-cosmetic head and neck conditions–An evidence based review

KH Awan - Saudi Pharmaceutical Journal, 2017 - Elsevier
Botulinum toxin (Botox) is an exotoxin produced from Clostridium botulinum. It blocks the
release of acetylcholine from the cholinergic nerve end plates resulting in inactivity of the …

[HTML][HTML] Suppl 4: Low Level Laser Therapy (LLLT) for Neck Pain: A Systematic Review and Meta-Regression

AR Gross, S Dziengo, O Boers… - The open …, 2013 - ncbi.nlm.nih.gov
Purpose: This systematic review update evaluated low level laser therapy (LLLT) for adults
with neck pain. Methods: Computerized searches (root up to Feb 2012) included pain …