Simulating microdosimetry in a virtual hepatic lobule
J Wambaugh, I Shah - PLoS computational biology, 2010 - journals.plos.org
The liver plays a key role in removing harmful chemicals from the body and is therefore often
the first tissue to suffer potentially adverse consequences. To protect public health it is …
the first tissue to suffer potentially adverse consequences. To protect public health it is …
Systems toxicology from genes to organs
This unique overview of systems toxicology methods and techniques begins with a brief
account of systems thinking in biology over the last century. We discuss how systems …
account of systems thinking in biology over the last century. We discuss how systems …
Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles
Background With increasing knowledge about the potential mechanisms underlying cellular
functions, it is becoming feasible to predict the response of biological systems to genetic and …
functions, it is becoming feasible to predict the response of biological systems to genetic and …
[图书][B] New models for the in vitro study of liver toxicity: 3D culture systems and the role of bioreactors
G Mazzoleni, N Steimberg - 2012 - academia.edu
Present in all animal species, even if less developed in the lowest classes of the animal
kingdom, the liver fulfils many vital functions of the utmost importance for the organism's …
kingdom, the liver fulfils many vital functions of the utmost importance for the organism's …