Carcinogenic effects of areca nut and its metabolites: a review of the experimental evidence

K Senevirathna, R Pradeep, YA Jayasinghe… - Clinics and …, 2023 - mdpi.com
Oral cancers (OC) are among the most frequent malignancies encountered in Southeast
Asia, primarily due to the prevalent habit of betel quid (BQ) and smokeless tobacco use in …

Areca nut–A gift by nature but a sweet poison for oral environment: A comprehensive review

N Aga, A Vanka, R Shreevats, S Gupta… - AYU (An International …, 2023 - journals.lww.com
Background: Nature provides us with a diversity of plants and fruits. These organic plants
and the products they produce might have some therapeutic potential that can be applied to …

Effects of herpes simplex virus type 1 infection on immune functions of human neutrophils

SL Hung, HH Chiang, CY Wu, MJ Hsu… - Journal of periodontal …, 2012 - Wiley Online Library
Hung S‐L, Chiang H‐H, Wu C‐Y, Hsu M‐J, Chen Y‐T. Effects of herpes simplex virus type 1
infection on immune functions of human neutrophils. J Periodont Res 2012; 47: 635–644.© …

Areca nut extracts increased the expression of cyclooxygenase-2, prostaglandin E2 and interleukin-1α in human immune cells via oxidative stress

LY Chang, HC Wan, YL Lai, IC Chou, YT Chen… - Archives of Oral …, 2013 - Elsevier
Background and objectives Areca nut has been identified as a carcinogen. Inflammation
reveals a strong link with tumourigenesis. The aim of this study was to investigate the effects …

[HTML][HTML] Risk factors for the development of oral precancerous lesions in a cohort of 293 oral lichen planus patients with or without chronic periodontitis in southern …

HY Huang, PY Lin, CC Chen, YK Chen - Journal of Dental Sciences, 2024 - Elsevier
Background/purpose Oral lichen planus (OLP) may contribute to the risk of chronic
periodontitis, and no reports have shown whether OLP patients with periodontitis have a …

Long‐term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity

CY Yen, WF Chiang, SY Liu, PC Cheng… - Journal of oral …, 2014 - Wiley Online Library
Background We previously demonstrated the autophagy‐inducing activity in the crude
extract of areca nut (ANE) and its 30–100 kDa fraction (ANE 30–100 K). This study aimed to …

[PDF][PDF] Betel nut chewing associated with severe periodontitis

DK Giri, P Kundapur, KM Bhat, IK Maharjan - Health Renaissance, 2014 - academia.edu
Betel quid chewing has been in practice among people in many Asian countries since ages.
It is the most widely used psychoactive substance and an important environmental risk factor …

Effects of areca nut extract on lipopolysaccharides‐enhanced adhesion and migration of human mononuclear leukocytes

LY Chang, YL Lai, TH Yu, YT Chen… - Journal of …, 2014 - Wiley Online Library
Background: Areca chewers have a higher prevalence of periodontitis than non‐chewers.
Cell adhesion and movement (migration) are important for leukocyte recruitment to …

Inhibitory effects of areca nut extract on expression of complement receptors and Fc receptors in human neutrophils

YY Lee, MB Lin, CF Cheng, LY Chang… - Journal of …, 2014 - Wiley Online Library
Background: Chewing of areca quid increases the prevalence of periodontal diseases.
Areca nut extract (ANE) inhibits the phagocytic activity of human neutrophils. This in vitro …

臺灣社群牙周病情況與面臨之挑戰

賴弘明 - 臺灣牙周病醫學會雜誌, 2013 - airitilibrary.com
臺灣在2007~ 2008 以國際常用之社群牙周與附連喪失指數(CPI and LA) 指數調查18
歲以上成年人之牙周病情況. 發現99% 有不等程度之牙周病, 54% 有牙周囊袋 …