SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022 - frontiersin.org
With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2
variants was inevitable. Several mutations have been identified in the SARS-CoV-2 …

CRISPR systems for COVID-19 diagnosis

H Rahimi, M Salehiabar, M Barsbay, M Ghaffarlou… - ACS …, 2021 - ACS Publications
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019,
which has spread rapidly and become a global pandemic. The number of cases of COVID …

Omicron BA. 2 (B. 1.1. 529.2): high potential for becoming the next dominant variant

J Chen, GW Wei - The journal of physical chemistry letters, 2022 - ACS Publications
The Omicron variant has three subvariants: BA. 1 (B. 1.1. 529.1), BA. 2 (B. 1.1. 529.2), and
BA. 3 (B. 1.1. 529.3). BA. 2 is found to be able to alarmingly reinfect patients originally …

New coronavirus variants are creating more challenges to global healthcare system: a brief report on the current knowledge

S Islam, T Islam, MR Islam - Clinical pathology, 2022 - journals.sagepub.com
The coronavirus is naturally mutating over time and producing new variants. Some of them
are more contagious and destructive than previous strains. Also, some variants are capable …

Preparation and characterization of B, S, and N-doped glucose carbon dots: Antibacterial, antifungal, and antioxidant activity

P Ezati, JW Rhim, R Molaei, R Priyadarshi… - Sustainable Materials …, 2022 - Elsevier
Carbon dots are prepared using glucose as a carbon source (GCD) and doped with
heteroatoms such as boron, sulfur, and nitrogen to enhance their functionality. FTIR and …

Estimate false‐negative RT‐PCR rates for SARS‐CoV‐2. A systematic review and meta‐analysis

V Pecoraro, A Negro, T Pirotti… - European journal of …, 2022 - Wiley Online Library
Background Molecular‐based tests used to identify symptomatic or asymptomatic patients
infected by SARS‐CoV‐2 are characterized by high specificity but scarce sensitivity …

Machine learning based clinical decision support system for early COVID-19 mortality prediction

A Karthikeyan, A Garg, PK Vinod… - Frontiers in public …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by the virus SARS-CoV-2, is an acute
respiratory disease that has been classified as a pandemic by the World Health …

Emerging vaccine-breakthrough SARS-CoV-2 variants

R Wang, J Chen, Y Hozumi, C Yin… - ACS infectious …, 2022 - ACS Publications
The surge of COVID-19 infections has been fueled by new SARS-CoV-2 variants, namely
Alpha, Beta, Gamma, Delta, and so forth. The molecular mechanism underlying such surge …

Hematological and biochemical parameters as diagnostic and prognostic markers in SARS-COV-2 infected patients of Pakistan: a retrospective comparative analysis

A Khalid, M Ali Jaffar, T Khan, R Abbas Lail, S Ali… - …, 2021 - Taylor & Francis
Objectives: This study was conducted to investigate alteration in blood parameters and their
association with the presence, severity, and mortality of COVID-19 patients as the data on …

Isothermal amplification-assisted diagnostics for COVID-19

M De Felice, M De Falco, D Zappi, A Antonacci… - Biosensors and …, 2022 - Elsevier
The scenery of molecular diagnostics for infectious diseases is rapidly evolving to respond
to the COVID-19 epidemic. The sensitivity and specificity of diagnostics, along with speed …