Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

Role of miRNAs in melanoma metastasis

A Gajos-Michniewicz, M Czyz - Cancers, 2019 - mdpi.com
Tumour metastasis is a multistep process. Melanoma is a highly aggressive cancer and
metastasis accounts for the majority of patient deaths. microRNAs (miRNAs) are non-coding …

High-performance strategy for the construction of electrochemical biosensor for simultaneous detection of miRNA-141 and miRNA-21 as lung cancer biomarkers

A Khodadoust, N Nasirizadeh, SM Seyfati, RA Taheri… - Talanta, 2023 - Elsevier
In this study, the dual signal-labeled hairpin-structured DNA (dhDNA)-based probes have
been developed to construct a novel nano-biosensor. This one hairpin-structured probe …

[HTML][HTML] The regulatory role of autophagy-related miRNAs in lung cancer drug resistance

M Shahverdi, K Hajiasgharzadeh, AD Sorkhabi… - Biomedicine & …, 2022 - Elsevier
Autophagy is conserved cellular machinery that degrades un-usable proteins and cellular
components and has a crucial role in the pathogenesis and drug resistance of various …

Diabetic nephropathy: the regulatory interplay between epigenetics and microRNAs

H Sankrityayan, YA Kulkarni, AB Gaikwad - Pharmacological research, 2019 - Elsevier
Diabetic nephropathy (DN) is still one of the leading causes of end-stage renal disease
despite the emergence of different therapies to counter the metabolic, hemodynamic and …

miR‐203 inhibits cell proliferation, invasion, and migration of non‐small‐cell lung cancer by downregulating RGS 17

Y Chi, Q Jin, X Liu, L Xu, X He, Y Shen, Q Zhou… - Cancer …, 2017 - Wiley Online Library
Involvement of the RGS 17 oncogene in the promotion of non‐small‐cell lung cancer
(NSCLC) has been reported, but the regulation mechanism in NSCLC remains unclear …

Electrochemical nano-biosensors as novel approach for the detection of lung cancer-related MicroRNAs

R Sheervalilou, O Shahraki… - Current molecular …, 2020 - ingentaconnect.com
In both men and women around the world, lung cancer accounts as the principal cause of
cancer-related death after breast cancer. Therefore, early detection of the disease is a …

[HTML][HTML] Epigenetics and Epi-miRNAs: Potential markers/therapeutics in leukemia

F Memari, Z Joneidi, B Taheri, SF Aval… - Biomedicine & …, 2018 - Elsevier
Epigenetic variations can play remarkable roles in different normal and abnormal situations.
Such variations have been shown to have a direct role in the pathogenesis of various …

MicroRNA-29a may influence myopia development by regulating collagen I

Y Zhu, Y Zhang, R Jiang, K Zhao, J Zhou - Current Eye Research, 2022 - Taylor & Francis
Purpose The aim of this study was to characterize the regulatory role of microRNA-29a (miR-
29a) in myopia, providing support for potential biomarkers and new therapeutic targets of …

A new insight on serum microRNA expression as novel biomarkers in breast cancer patients

Z Bahmanpour, R Sheervalilou… - Journal of Cellular …, 2019 - Wiley Online Library
Breast cancer (BC) is one of the widespread lethal diseases affecting a large number of
women worldwide. As such, employing and identifying significant markers for detecting BC …