We aimed to conduct a review of the literature for gene polymorphisms associated with
chronic periodontitis (CP) susceptibility. A comprehensive search of the literature in English …

Aim: We conducted a systematic review and a meta‐analysis, in order to investigate the
potential association of cytokine gene polymorphisms with either aggressive or chronic …

Background: Interleukin‐1 (IL‐1) gene polymorphisms have been associated with increased
levels of inflammatory mediators and several inflammatory diseases. Periodontitis is a …

Aim Periodontitis is an inflammatory disease that destroys both soft and hard periodontal
tissues. However, a complex periodontal cytokine network remains unclear. This systematic …

Aim Tumour necrosis factor‐alpha (TNF‐α) plays a critical role in the pathogenesis of
periodontal disease. TNF‐α gene polymorphisms can influence the TNF‐α production. Many …

Background Chronic periodontitis (CP), defines as destruction of the supporting tissues of
the teeth and resorption of the alveolar bone. It is widespread in human populations and …

Background and objective Although the association between tumor necrosis factor‐α (TNF‐
α) G‐308A (rs1800629) polymorphism and chronic periodontitis (CP), chronic periodontitis …

Host genetic predispositions to dysregulated immune response can influence the
development of the aggressive form of periodontitis (AgP) through susceptibility to oral …

Several factors are involved in the periodontitis with host response through cytokines and as
well as with influence of polymorphisms in cytokine genes, however the results remained …

Background: Periodontitis is a very common inflammatory oral disease. Tumor necrosis
factor-α (TNF-α) is a cytokine that has been involved with the gingival tissue destruction and …