Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

Diabetic cardiomyopathy is a common cardiac condition in patients with diabetes mellitus,
which can result in cardiac hypertrophy and subsequent heart failure, associated with …

MicroRNAs (miRs) are small RNAs that regulate gene expression at the posttranscriptional
level. miR-27 is expressed in endothelial cells, but the specific functions of miR-27b and its …

Recent studies have begun to reveal critical roles of microRNAs (miRNAs) in the
pathogenesis of cardiac hypertrophy and dysfunction. In this study, we tested whether a …

In 1993, lin-4 was discovered as a critical modulator of temporal development in
Caenorhabditis elegans and, most notably, as the first in the class of small, single-stranded …

Heart failure (HF) imposes significant economic and public health burdens upon modern
society. It is known that disturbances in neurohormonal status play an important role in the …

Coronary artery disease and acute myocardial infarction (AMI) are the leading causes of
death for both men and women. Serum cardiac-specific troponin level is now used for the …

MicroRNAs (miRNAs) are small non-coding RNAs that control expression of complementary
target mRNAs. A growing number of miRNAs has been implicated in the pathogenesis of …

Background The microRNAs have been implicated in the process of cardiac development,
cardiac hypertrophy, and heart failure. However, the impact of adult aging on cardiac …