Trends in current epidemiological data suggest that the incidence of inflammatory bowel
diseases is changing. Eastern Europe previously was seen as a low incidence area; …

Background Previous studies have demonstrated that serological markers can assist in
diagnosing inflammatory bowel disease (IBD). In this study, we aim to build a diagnostic tool …

Background Patients with inflammatory bowel disease (IBD) are at higher risk for Clostridium
difficile infection (CDI). Disruption of gut microbiome and interaction with the intestinal …

Strong evidence indicates that inflammatory bowel disease, including Crohn disease and
ulcerative colitis, is a result of an inappropriate inflammatory response in which genetic and …

Background Recent European ancestry genome-wide association studies have identified
genetic variants of IRGM as significant susceptibility loci for Crohn's disease (CD) …

Background Polymorphisms in immunity-related GTPase family M (IRGM) gene may be
associated with inflammatory bowel disease (IBD) by affecting autophagy. However, the …

Background: About 70 loci are associated with susceptibility to Crohn's disease (CD),
particularly in pathways of innate immunity, autophagy, and pathogen recognition …

Background Mutations in the IRGM gene have been associated with Crohn's disease in
several populations but have not been explored in Indian patients with this disease. This …

Aim To investigate the association between known inflammatory bowel disease (IBD)-
associated genetic variants and development of paediatric IBD, and specific clinical sub …

Background Crohn's disease (CD) and Ulcerative colitis (UC) are the two main entities of
inflammatory bowel disease (IBD). Previous works have identified more than 200 risk factors …