Quality by design prospects of pharmaceuticals application of double emulsion method for PLGA loaded nanoparticles

D Panigrahi, PK Sahu, S Swain, RK Verma - SN applied sciences, 2021 - Springer
QbD approach empowers the pharma researchers to minimize the number of experimental
trials and time. It helps identify the significant, influential factors such as critical material …

Recent advances in nanotechnology for the treatment of melanoma

R Cassano, M Cuconato, G Calviello, S Serini… - Molecules, 2021 - mdpi.com
Melanoma is one of the most aggressive forms of skin cancer, with few possibilities for
therapeutic approaches, due to its multi-drug resistance and, consequently, low survival rate …

Polymeric nanomaterial strategies to encapsulate and deliver biological drugs: points to consider between methods

X Chen, Y Wu, NT Nguyen, HT Ta - Biomaterials Science, 2023 - pubs.rsc.org
Biological drugs (BDs) play an increasingly irreplaceable role in treating various diseases
such as cancer, and cardiovascular and neurodegenerative diseases. The market share of …

Antitumor effect of hyperoside loaded in charge reversed and mitochondria-targeted liposomes

Y Feng, G Qin, S Chang, Z Jing, Y Zhang… - International Journal of …, 2021 - Taylor & Francis
Introduction Hyperoside (HYP), a flavonol glycoside compound, has been shown to
significantly inhibit the proliferation of malignant tumors. Mitochondria serve as both “energy …

TAT for enzyme/protein delivery to restore or destroy cell activity in human diseases

M Lichtenstein, S Zabit, N Hauser, S Farouz, O Melloul… - Life, 2021 - mdpi.com
Much effort has been dedicated in the recent decades to find novel protein/enzyme-based
therapies for human diseases, the major challenge of such therapies being the intracellular …

Evaluation of paclitaxel-loaded polymeric nanoparticles in 3D tumor model: Impact of tumor stroma on penetration and efficacy

DL Priwitaningrum, K Pednekar, AV Gabriël… - Drug delivery and …, 2023 - Springer
Since tumor stroma poses as a barrier to achieve efficacy of nanomedicines, it is essential to
evaluate nano-chemotherapeutics in stroma-mimicking 3D models that reliably predict their …

Inhibitory Effects of Royal Jelly and Its Functional Components on the Proliferation of MKN-28 Gastric Cancer Cells

Y Ma, H Wang, X Hu, H Zou, T Xu, Z Wang… - Journal of Agricultural …, 2024 - ACS Publications
Royal jelly (RJ) is a natural food product with nutritional value and anticancer activity.
However, their effects on gastric cancer are unclear. Here, we show that treatment with 5 …

Development of silk fibroin/collagen film containing GI-20 peptide-loaded PLGA nanoparticles against corneal herpes simplex virus-1

R Sohrabi, AH Miri, M Rad-Malekshahi… - International Journal of …, 2025 - Elsevier
Abstract Herpes simplex virus-1 (HSV-1) is the primary cause of infectious blindness.
Despite impressive therapeutic outcomes of conventional treatments, HSV-1 drug resistance …

Unlocking nature's arsenal: Nanotechnology for targeted delivery of venom toxins in cancer therapy

PS Chary, S Shaikh, N Rajana, V Bhavana… - Biomaterials …, 2024 - Elsevier
Aim The aim of the present review is to shed light on the nanotechnological approaches
adopted to overcome the shortcomings associated with the delivery of venom peptides …

Cyclic β-hairpin peptide loaded PLGA nanoparticles: A potential anti-amyloid therapeutic

BD Khairnar, A Padhye, V Madiwal, A Jha… - Materials Today …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by β-
amyloid peptide (Aβ 1–42) deposits, with no definitive therapies. Recently, cyclic peptides …