In the high-stakes arena of drug discovery, the journey from bench to bedside is hindered by
a daunting 92% failure rate, primarily due to unpredicted toxicities and inadequate …

Exposure to heavy metals in various populations can lead to extensive damage to different
organs, as these metals infiltrate and bioaccumulate in the human body, causing metabolic …

This study aimed to develop novel primer-probe sets specifically optimized for detecting E.
coli and E. coli O157 through comparative genomic analysis. Genomic data from 2396 E …

Cardiovascular diseases are the leading cause of mortality worldwide, with a
disproportionately high burden in low-and middle-income countries. Biomarkers play a …

Chronic kidney disease (CKD) is closely linked to the aging process, making the
identification of protein biomarkers that reflect aging in specific organs and tissues crucial for …

Objective: To systematically identify early biomarkers of cisplatin-induced acute kidney injury
(AKI) in rats. Study Design: An experimental study. Place and Duration of the Study …

High-sensitivity nanoflow liquid chromatography (nLC) is seldom employed in untargeted
metabolomics because current sample preparation techniques are inefficient at preventing …

Cardiovascular diseases are the leading cause of mortality worldwide, with a
disproportionately high burden in low-and middle-income countries. Biomarkers play a …