Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Although mortality rates from coronary heart disease in the western countries have declined
in the last few decades, morbidity caused by this disease is increasing and a substantial …

Atherosclerosis is driven by multifaceted contributions of the immune system within the
circulation and at vascular focal sites. However, specific characteristics of dysregulated …

OBJECTIVE: Macrophages are decisive in the chronic inflammatory processes that drive
atherogenesis. The purpose of this study was to explore the presence and spatial …

Today's concept of vulnerable plaque has evolved primarily from the early pioneering work
uncovering the pivotal role of plaque rupture and coronary thrombosis as the major cause of …

Inflammation, Atherosclerosis, and Coronary Artery Disease | New England Journal of Medicine
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Significance: A growing body of clinical and experimental evidence has challenged the
traditional understanding that only the adaptive immune system can mount immunological …

Coronary atherosclerosis is by far the most frequent cause of ischemic heart disease, and
plaque disruption with superimposed thrombosis is the main cause of the acute coronary …

Atherosclerosis is the underlying reason for nearly all causes of coronary artery disease and
peripheral arterial disease and many cases of stroke. Atherosclerosis is a systemic …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …