Epilepsy involves neuronal dysfunction at molecular, cellular, and circuit levels. The
understanding of the mechanism of the epilepsies has advanced greatly in the last three …

Epilepsy, one of the most severe neurological diseases, is characterized by abrupt recurrent
seizures. Despite great progress in the development of antiseizure drugs (ASDs) based on …

Epilepsy is a group of chronic neurological disorders characterized with recurrent and
hypersynchronous discharge. In the epileptic brain, epileptogenic zone (EZ) with abnormal …

Low-frequency stimulation (LFS) has been considered as an option for the treatment of
intractable epilepsy. However, previous data showed that LFS of certain brain regions only …

High-frequency stimulation (HFS) of the anterior nucleus of thalamus (ANT) is a new and
alternative option for the treatment of intractable epilepsy. However, the responder rate is …

Temporal lobe epilepsy (TLE) is the most common epilepsy syndrome and is often
associated with pharmacoresistance. Patients with pharmacoresistant TLE may be …

Many patients with epilepsy do not obtain proper control of their seizures through
conventional treatment. We review aspects of the pathophysiology underlying epileptic …

Mesial temporal lobe epilepsy (MTLE) is a common medically refractory neurological
disease that has been treated with electrical stimulation of gray matter with limited success …

This study investigated neurotoxicity of chronic fluorosis in the rat hippocampus. Newly
weaning, male, Sprague-Dawley (SD) rats were administered 15, 30, and 60 mg/L sodium …

癫痫是神经系统疾病中最常见的慢性脑部疾病之一, 根据国际抗癫痫联盟(ILAE)
公布的统计数据, 人群中1% 在一生中可能有过至少1 次抽搐, 但只有持续存在着产生癫痫反复 …