Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic
lung disease and predisposes individuals to acute lung injury and pulmonary infection …

It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …

Abstract Background Polymorphonuclear neutrophils (PMNs) play an important role in
sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived …

Macrophages, circulating in the blood or concatenated into different organs and tissues
constitute the first barrier against any disease. They are foremost controllers of both innate …

The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …

ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …

Abstract Background Systemic sclerosis (SSc) is a disorder characterized by immune system
alterations, vasculopathy and fibrosis. SSc-related interstitial lung disease (ILD) represents a …

Neutrophils activated during acute lung injury (ALI) form neutrophil extracellular traps
(NETs) to capture pathogens. However, excessive NETs can cause severe inflammatory …

Chronic exposure to indoor biomass smoke from the combustion of solid organic fuels is a
major cause of disease burden worldwide. Almost 3 billion people use solid fuels such as …