Understanding nanomaterial–liver interactions to facilitate the development of safer nanoapplications

J Li, C Chen, T Xia - Advanced Materials, 2022 - Wiley Online Library
Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …

Cerium oxide nanoparticles: advances in biodistribution, toxicity, and preclinical exploration

E Casals, M Zeng, M Parra‐Robert, G Fernández‐Varo… - Small, 2020 - Wiley Online Library
Antioxidant nanoparticles have recently gained tremendous attention for their enormous
potential in biomedicine. However, discrepant reports of either medical benefits or toxicity …

Multicenter validation of association between decline in MRI‐PDFF and histologic response in NASH

R Loomba, BA Neuschwander‐Tetri, A Sanyal… - Hepatology, 2020 - journals.lww.com
Bespoken Nanoceria: An Effective Treatment in Experimental H... : Hepatology Bespoken
Nanoceria: An Effective Treatment in Experimental Hepatocellular Carcinoma : Hepatology …

All roads lead to the liver: metal nanoparticles and their implications for liver health

A Boey, HK Ho - Small, 2020 - Wiley Online Library
Metal nanoparticles (NPs) are frequently encountered in daily life, and concerns have been
raised about their toxicity and safety. Among which, they naturally accumulate in the liver …

Cerium oxide nanoparticles: a new therapeutic tool in liver diseases

G Casals, M Perramón, E Casals, I Portolés… - Antioxidants, 2021 - mdpi.com
Oxidative stress induced by the overproduction of free radicals or reactive oxygen species
(ROS) has been considered as a key pathogenic mechanism contributing to the initiation …

The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State‐of‐the‐Art Review

SA Moosavian, T Sathyapalan… - Bioinorganic …, 2021 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can lead to
end‐stage liver disease needing a liver transplant. Many pharmacological approaches are …

Design of hepatic targeted drug delivery systems for natural products: insights into nomenclature revision of nonalcoholic fatty liver disease

R Tang, R Li, H Li, XL Ma, P Du, XY Yu, L Ren… - Acs Nano, 2021 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-dysfunction-
associated fatty liver disease (MAFLD), affects a quarter of the worldwide population. Natural …

[PDF][PDF] Bespoken nanoceria: an effective treatment in experimental hepatocellular carcinoma

G Fernández‐Varo, M Perramón, S Carvajal… - …, 2020 - Wiley Online Library
Background and Aims Despite the availability of new‐generation drugs, hepatocellular
carcinoma (HCC) is still the third most frequent cause of cancer‐related deaths worldwide …

Nanodrug delivery systems for metabolic chronic liver diseases: advances and perspectives

F Athanasopoulou, M Manolakakis, S Vernia… - …, 2023 - Taylor & Francis
Nanomedicines are revolutionizing healthcare as recently demonstrated by the
Pfizer/BioNTech and Moderna COVID-2019 vaccines, with billions of doses administered …

Proteomics revealed composition-and size-related regulators for hepatic impairments induced by silica nanoparticles

X Zhao, R Ma, A Abulikemu, Y Qi, X Liu, J Wang… - Science of The Total …, 2024 - Elsevier
Along with the growing production and application of silica nanoparticles (SiNPs), increased
human exposure and ensuing safety evaluation have progressively attracted concern …