ISFETs in CMOS and emergent trends in instrumentation: A review

N Moser, TS Lande, C Toumazou… - IEEE Sensors …, 2016 - ieeexplore.ieee.org
Over the past decade, ion-sensitive field-effect transistors (ISFETs) have played a major role
in enabling the fabrication of fully integrated CMOS-based chemical sensing systems. This …

Wireless integrated biosensors for point-of-care diagnostic applications

E Ghafar-Zadeh - Sensors, 2015 - mdpi.com
Recent advances in integrated biosensors, wireless communication and power harvesting
techniques are enticing researchers into spawning a new breed of point-of-care (POC) …

Simultaneous DNA amplification and detection using a pH-sensing semiconductor system

C Toumazou, LM Shepherd, SC Reed, GI Chen… - Nature …, 2013 - nature.com
We developed an integrated chip for real-time amplification and detection of nucleic acid
using pH-sensing complementary metal-oxide semiconductor (CMOS) technology. Here we …

16-channel CMOS impedance spectroscopy DNA analyzer with dual-slope multiplying ADCs

H Jafari, L Soleymani, R Genov - IEEE transactions on …, 2012 - ieeexplore.ieee.org
We present a 16-channel, mixed-signal CMOS DNA analyzer that utilizes frequency
response analysis (FRA) to extract the real and imaginary impedance components of the …

ISFET-based sensing and electric field actuation of DNA for on-chip detection: A review

L Keeble, N Moser, J Rodriguez-Manzano… - IEEE Sensors …, 2020 - ieeexplore.ieee.org
The advent of complementary metal-oxide-semiconductor (CMOS) based lab-on-chip (LoC)
technology, which combines on-chip sample handling with integrated sensing, heralds the …

A differential electrochemical readout ASIC with heterogeneous integration of bio-nano sensors for amperometric sensing

SS Ghoreishizadeh, I Taurino… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
A monolithic biosensing platform is presented for miniaturized amperometric
electrochemical sensing in CMOS. The system consists of a fully integrated current readout …

A 12.8 k current-mode velocity-saturation ISFET array for on-chip real-time DNA detection

N Miscourides, LS Yu… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents a large-scale CMOS chemicalsensing array operating in current mode
for real-time ion imaging and detection of DNA amplification. We show that the currentmode …

An extended CMOS ISFET model incorporating the physical design geometry and the effects on performance and offset variation

Y Liu, P Georgiou, T Prodromakis… - … on Electron Devices, 2011 - ieeexplore.ieee.org
This paper presents an extended model for the CMOS-based ion-sensitive field-effect
transistor, incorporating design parameters associated with the physical geometry of the …

Nanostructured CMOS wireless ultra-wideband label-free PCR-free DNA analysis SoC

HM Jafari, K Abdelhalim, L Soleymani… - IEEE Journal of Solid …, 2014 - ieeexplore.ieee.org
A fully integrated 54-channel wireless fast-scan cyclic voltammetry DNA analysis SoC is
presented. The microsystem includes 546 3D nanostructured and 54 2D gold DNA sensing …

ISFET arrays in CMOS: A head-to-head comparison between voltage and current mode

N Miscourides, P Georgiou - IEEE Sensors Journal, 2018 - ieeexplore.ieee.org
This paper demonstrates and compares three configurations for ISFET arrays fabricated in
unmodified CMOS that facilitate chemical imaging with linear pH-to-output conversion …