[PDF][PDF] The biology of PECAM-1.

PJ Newman - The Journal of clinical investigation, 1997 - Am Soc Clin Investig
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kD member of the
immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets …

CD31 as a therapeutic target in atherosclerosis

G Caligiuri - Circulation Research, 2020 - Am Heart Assoc
The potential of CD31 as a therapeutic target in atherosclerosis has been considered ever
since its cloning in the 1990s, but the exact role played by this molecule in the biologic …

[HTML][HTML] The unfolding tale of PECAM-1

DE Jackson - FEBS letters, 2003 - Elsevier
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) is a member of the
immunoglobulin (Ig) superfamily that has distinctive features of an immunoreceptor based …

CD31 expression in intratumoral macrophages: a potential diagnostic pitfall

JK McKenney, SW Weiss, AL Folpe - The American journal of …, 2001 - journals.lww.com
CD31 (platelet endothelial adhesion molecule, PECAM-1) is generally regarded to be the
most sensitive and specific endothelial marker in paraffin sections. We have recently …

Inflammatory gene polymorphisms and ischaemic heart disease: review of population association studies

F Andreotti, I Porto, F Crea, A Maseri - Heart, 2002 - heart.bmj.com
Inflammation and genetics are both prominent mechanisms in the pathogenesis of
atherosclerosis and arterial thrombosis. Accordingly, a number of population studies have …

CD31 and VEGF are prognostic biomarkers in early-stage, but not in late-stage, laryngeal squamous cell carcinoma

A Schlüter, P Weller, O Kanaan, I Nel, L Heusgen… - BMC cancer, 2018 - Springer
Background Patients suffering from squamous cell carcinoma of the larynx (LSCC) with
lymphatic metastasis have a relatively poor prognosis and often require radical therapeutic …

Role of platelets in neuroinflammation: a wide-angle perspective

LL Horstman, W Jy, YS Ahn, R Zivadinov… - Journal of …, 2010 - Springer
Objectives This review summarizes recent developments in platelet biology relevant to
neuroinflammatory disorders. Multiple sclerosis (MS) is taken as the" Poster Child" of these …

Targeting of antioxidant and anti-thrombotic drugs to endothelial cell adhesion molecules

S Muro, VR Muzykantov - Current pharmaceutical design, 2005 - ingentaconnect.com
The endothelium represents an important therapeutic target for containment of oxidative
stress, thrombosis and inflammation involved in a plethora of acute and chronic conditions …

The effects of tissue healing factors in wound repair involving absorbable meshes: A narrative review

V Vasalou, E Kotidis, D Tatsis, K Boulogeorgou… - Journal of Clinical …, 2023 - mdpi.com
Wound healing is a complex and meticulously orchestrated process involving multiple
phases and cellular interactions. This narrative review explores the intricate mechanisms …

PECAM‐1, a key player in neuroinflammation

A Kalinowska, J Losy - European journal of neurology, 2006 - Wiley Online Library
Platelet endothelial cell adhesion molecule‐1 (PECAM‐1, CD31) is a 130‐kDa protein,
which plays a significant role in the adhesion cascade. It is therefore involved in leucocyte …