Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project

E Ong, LL Wang, J Schaub, JF O'Toole… - Nature Reviews …, 2020 - nature.com
An important need exists to better understand and stratify kidney disease according to its
underlying pathophysiology in order to develop more precise and effective therapeutic …

Excess mortality in the first COVID pandemic peak: cross-sectional analyses of the impact of age, sex, ethnicity, household size, and long-term conditions in people of …

M Joy, FDR Hobbs, JL Bernal, J Sherlock… - British Journal of …, 2020 - bjgp.org
Background The SARS-CoV-2 pandemic has passed its first peak in Europe. Aim To
describe the mortality in England and its association with SARS-CoV-2 status and other …

[HTML][HTML] COVID-19 surveillance in a primary care sentinel network: in-pandemic development of an application ontology

S de Lusignan, H Liyanage, D McGagh… - JMIR public health …, 2020 - publichealth.jmir.org
Background: Creating an ontology for COVID-19 surveillance should help ensure
transparency and consistency. Ontologies formalize conceptualizations at either the domain …

[HTML][HTML] Disparities in the excess risk of mortality in the first wave of COVID-19: cross sectional study of the English sentinel network

S De Lusignan, M Joy, J Oke, D McGagh, B Nicholson… - Journal of Infection, 2020 - Elsevier
Objectives Few studies report contributors to the excess mortality in England during the first
wave of coronavirus disease 2019 (COVID-19) infection. We report the absolute excess risk …

EHR-oriented knowledge graph system: toward efficient utilization of non-used information buried in routine clinical practice

Y Shang, Y Tian, M Zhou, T Zhou, K Lyu… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Non-used clinical information has negative implications on healthcare quality. Clinicians pay
priority attention to clinical information relevant to their specialties during routine clinical …

[HTML][HTML] FAIRVASC: A semantic web approach to rare disease registry integration

K McGlinn, MA Rutherford, K Gisslander… - Computers in Biology …, 2022 - Elsevier
Rare disease data is often fragmented within multiple heterogeneous siloed regional
disease registries, each containing a small number of cases. These data are particularly …

Implementation of chronic kidney disease guidelines for sodium-glucose co-transporter-2 inhibitor use in primary care in the UK: a cross-sectional study

AK Forbes, W Hinton, MD Feher, W Elson, M Joy… - …, 2024 - thelancet.com
Background The cardiovascular and kidney benefits of sodium-glucose co-transporter-2
(SGLT2) inhibitors in people with chronic kidney disease (CKD) are well established. The …

A drug prescription recommendation system based on novel DIAKID ontology and extensive semantic rules

K Göğebakan, R Ulu, R Abiyev, M Şah - Health Information Science and …, 2024 - Springer
Abstract According to the World Health Organization (WHO) data from 2000 to 2019, the
number of people living with Diabetes Mellitus and Chronic Kidney Disease (CKD) is …

Global health inequalities of chronic kidney disease: a meta-analysis

R Duff, O Awofala, MT Arshad… - Nephrology Dialysis …, 2024 - academic.oup.com
Background Chronic kidney disease (CKD) is a significant contributor to global morbidity
and mortality. This study investigated disparities in age, sex and socio-economic status in …

Prescribing sodium-glucose co-transporter-2 inhibitors for type 2 diabetes in primary care: influence of renal function and heart failure diagnosis

W Hinton, MD Feher, N Munro, M Joy… - Cardiovascular …, 2021 - Springer
Background Sodium-glucose co-transporter-2 inhibitors (SGLT-2is) are licenced for initiation
for glucose lowering in people with type 2 diabetes (T2DM) with an estimated glomerular …