Advances in polysaccharides of natural source of the anti-Alzheimer's disease effect and mechanism

Z Zhang, S Wang, H Tan, P Yang, Y Li, L Xu… - Carbohydrate …, 2022 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative disorder. The pathology is
characterized by the generation of amyloid plaques and neuronal fiber tangles in the brain …

[HTML][HTML] Panax Ginseng in the treatment of Alzheimer's disease and vascular dementia

Z Wang, Z Zhang, J Liu, M Guo, H Li - Journal of Ginseng Research, 2023 - Elsevier
Dementia has become one of the most important diseases threatening human health.
Alzheimer's disease (AD) and vascular dementia (VaD) have the highest incidence rates …

[HTML][HTML] Phytotherapy: A promising approach for the treatment of Alzheimer's disease

OO John, IS Amarachi, AP Chinazom, E Adaeze… - Pharmacological …, 2022 - Elsevier
Alzheimer's disease (AD) is a progressive neurological disease and the most common form
of dementia, affecting more than 10 million people all over the world. Clinically, AD is …

Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and …

M Hao, C Ding, X Peng, H Chen, L Dong, Y Zhang… - Phytomedicine, 2022 - Elsevier
Background Ginseng is deemed to be an effective anti-aging therapy. Evidence for
differences in representative active ingredients and anti-aging effects between garden …

Investigating the impact of environmental enrichment on proteome and neurotransmitter‐related profiles in an animal model of Alzheimer's disease

Y Nam, S Kim, YH Park, BH Kim, SJ Shin, SH Leem… - Aging …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder associated with behavioral and
cognitive impairments. Unfortunately, the drugs the Food and Drug Administration currently …

Protective effects of polysaccharides in neurodegenerative diseases

Y Wang, R Chen, Z Yang, Q Wen, X Cao… - Frontiers in Aging …, 2022 - frontiersin.org
Neurodegenerative diseases (NDs) are characterized by progressive degeneration and
necrosis of neurons, including Alzheimer's disease (AD), Parkinson's disease (PD) …

[HTML][HTML] A novel mechanism of Korean Red Ginseng-mediated anti-inflammatory action via targeting caspase-11 non-canonical inflammasome in macrophages

JH Min, HJ Cho, YS Yi - Journal of Ginseng Research, 2022 - Elsevier
Abstract Background Korean Red Ginseng (KRG) was reported to play an anti-inflammatory
role, however, previous studies largely focused on the effects of KRG on priming step, the …

Isolation, structure, biological activity and application progress of ginseng polysaccharides from the Araliaceae family

S Liu, J Geng, W Chen, Y Zong, Y Zhao, R Du… - International Journal of …, 2024 - Elsevier
Phytopolysaccharides are a class of natural macromolecules with a range of biological
activities. Ginseng, red ginseng, American ginseng, and Panax notoginseng are all …

Neuroprotective potentials of Panax ginseng against Alzheimer's disease: a review of preclinical and clinical evidences

J Li, Q Huang, J Chen, H Qi, J Liu, Z Chen… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD), a neurodegenerative disorder, is a major health concern in the
increasingly aged population worldwide. Currently, no clinically effective drug can halt the …

[HTML][HTML] Platycodon grandiflorum root extract inhibits Aβ deposition by breaking the vicious circle linking oxidative stress and neuroinflammation in Alzheimer's …

Y Nam, YJ Ji, SJ Shin, HH Park, SH Yeon… - Biomedicine & …, 2024 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease accompanied by
irreversible cognitive impairment. A deleterious feedback loop between oxidative stress and …