The docking field has come of age. The time is ripe to present the principles of docking,
reviewing the current state of the field. Two reasons are largely responsible for the maturity …

Antibodies are an effective line of defense in preventing infectious diseases. Highly potent
neutralizing antibodies can intercept a virus before it attaches to its target cell and, thus …

Histone deacetylases (HDACs) play an important role in gene transcription. Inhibitors of
HDACs induce cell differentiation and suppress cell proliferation in tumor cells. Although …

The present work undertakes the study of a new hybrid material C 6 H 16 N 2 (NO 3) 2
symbolized as follows 1EPBN (1-Ethylpiperazine-1, 4-diium Bis (Nitrate)), a synergy …

Histone deacetylases (HDACs) play an important role in gene transcription. Inhibitors of
HDACs induce cell differentiation and suppress cell proliferation in tumor cells. AutoDock …

The application of the fields of pharmacogenomics and pharmacogenetics to vaccine
design, profoundly combined with bioinformatics, has been recently termed “vaccinomics.” …

Abstract Taste receptor T1R1-T1R3 can be activated by binding to several natural ligands,
eg, l-glutamate and 5′-ribonucleotides etc., thereby stimulating the umami taste. The …

Protein–protein binding is one of the critical events in biology, and knowledge of proteic
complexes three‐dimensional structures is of fundamental importance for the biochemical …

Docking algorithms that aim to be applicable to a broad range of ligands suffer reduced
accuracy because they are unable to incorporate ligand‐specific conformational energies …

Molecular organic dyes are classic fluorescent nanoprobes finding tremendous uses in
biological and life sciences. Yet, they suffer from low brightness, poor photostability, and lack …