Deterministic and probabilistic fate decisions co‐exist in a single retinal lineage

E Nerli, J Kretzschmar, T Bianucci… - The EMBO …, 2023 - embopress.org
Correct nervous system development depends on the timely differentiation of progenitor
cells into neurons. While the output of progenitor differentiation is well investigated at the …

Conservation of cis-Regulatory Syntax Underlying Deuterostome Gastrulation

L Buono, G Annona, MS Magri, S Negueruela… - Cells, 2024 - mdpi.com
Throughout embryonic development, the shaping of the functional and morphological
characteristics of embryos is orchestrated by an intricate interaction between transcription …

In Search of a Target Gene for a Desirable Phenotype in Aquaculture: Genome Editing of Cyprinidae and Salmonidae Species

SY Orlova, MN Ruzina, OR Emelianova, AA Sergeev… - Genes, 2024 - mdpi.com
Aquaculture supplies the world food market with a significant amount of valuable protein.
Highly productive aquaculture fishes can be derived by utilizing genome-editing methods …

Retinal Degeneration Response to Graphene Quantum Dots: Disruption of the Blood–Retina Barrier Modulated by Surface Modification-Dependent DNA Methylation

Y Liu, X Tan, R Wang, L Fan, Q Yan… - Environmental …, 2024 - ACS Publications
Graphene quantum dots (GQDs) are used in diverse fields from chemistry-related materials
to biomedicines, thus causing their substantial release into the environment. Appropriate …

[HTML][HTML] Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS

V Naef, D Damiani, R Licitra, M Marchese… - Neurobiology of …, 2025 - Elsevier
Biallelic mutations in the SACS gene, encoding sacsin, cause early-onset autosomal
recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disease …

Comparative single-cell transcriptomic analysis reveals key differentiation drivers and the potential origin of the vertebrate retina

X Zeng, F Gyoja, Y Cui, M Loza, TG Kusakabe, K Nakai - bioRxiv, 2023 - biorxiv.org
Background The retina plays a vital role in capturing and processing visual information in
vertebrates, allowing them to adapt to diverse environments. Single-cell expression profiles …

Control of Epithelial Morphogenesis in Vertebrates

JRM Morales - CABD Annual Report 2023 - cabd.es
Highlights of 2023 include two relevant publications and a new funded project. By analysing
the phenotype of yap1/yap1b double mutants in medaka fish,(O. latipes) we showed that …