Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Objective To incorporate recent research findings, expert consensus, and patient
perspectives into updated guidance on the use of new acute and preventive treatments for …

Importance Approximately 90% of people in the US experience headache during their
lifetime. Migraine is the second leading cause of years lived with disability worldwide …

Abstract Lasmiditan, a serotonin 5-HT1F receptor agonist, was effective for acute treatment
of patients with migraine in a phase 3 double-blind randomized controlled study. The current …

Migraine is a common, chronic, disorder that is typically characterized by recurrent disabling
attacks of headache and accompanying symptoms, including aura. The aetiology is …

Heart failure is a common, costly, and debilitating syndrome that is associated with a highly
complex drug regimen, a large number of comorbidities, and a large and often disparate …

Migraine continues second among the world's causes of disability. Diagnosis is based on
the history and clinical examination and imaging is usually not necessary. Migraine can be …

Migraine and stroke are two common and heterogeneous neurovascular disorders
responsible for a significant burden for those affected and a great economic cost for the …

Migraine is a debilitating disease whose clinical and social impact is out of debate.
Tolerability issues, interactions, contraindications, and inefficacy of the available …