Molecular pathways and targeted therapies for malignant ovarian germ cell tumors and sex cord–stromal tumors: a contemporary review

A Maoz, K Matsuo, MA Ciccone, S Matsuzaki, M Klar… - Cancers, 2020 - mdpi.com
Non-epithelial ovarian tumors are heterogeneous and account for approximately 10% of
ovarian malignancies. The most common subtypes of non-epithelial ovarian tumors arise …

Natural compounds and derivatives as Ser/Thr protein kinase modulators and inhibitors

B Guerra, OG Issinger - Pharmaceuticals, 2019 - mdpi.com
The need for new drugs is compelling, irrespective of the disease. Focusing on medical
problems in the Western countries, heart disease and cancer are at the moment …

[HTML][HTML] Acquired resistance to tyrosine kinase inhibitors may be linked with the decreased sensitivity to X-ray irradiation

M Sorokin, R Kholodenko, A Grekhova, M Suntsova… - Oncotarget, 2017 - oncotarget.com
Abstract Maxim Sorokin 1, 2, 3, Roman Kholodenko 3, Anna Grekhova 4, Maria Suntsova 1,
5, Margarita Pustovalova 4, Natalia Vorobyeva 1, 4, Irina Kholodenko 6, Galina Malakhova …

Clinical significance and prognostic value of lactate dehydrogenase expression in cervical cancer

Y Ye, M Chen, X Chen, J Xiao, L Liao… - Genetic testing and …, 2022 - liebertpub.com
Background: Lactate dehydrogenase (LDH) is a marker of injury and disease as it is
expressed extensively in numerous cell types and tissues. Moreover it is released during …

A comprehensive meta-analysis of transcriptome data to identify signature genes associated with pancreatic ductal adenocarcinoma

SO Kordshouli, A Tahmasebi, A Moghadam… - Plos one, 2024 - journals.plos.org
Purpose Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of less than
5%. Absence of symptoms at primary tumor stages, as well as high aggressiveness of the …

[HTML][HTML] Rare ovarian tumours. Other treatments for ovarian cancer

M Gil-Martin, B Pardo, MP Barretina-Ginesta - European Journal of Cancer …, 2020 - Elsevier
Aim The description of rare malignant ovarian tumours and the most suitable treatments.
Alternative therapies different from intravenous chemotherapy are also explained. Methods …

Radiotherapy for isolated recurrent epithelial ovarian cancer: a single institutional experience

N Komura, S Mabuchi, F Isohashi… - Journal of Obstetrics …, 2019 - Wiley Online Library
Aim To evaluate the efficacy and toxicity of external beam radiotherapy (RT) for isolated
recurrent epithelial ovarian cancer (EOC). Methods Twenty‐four isolated recurrent EOC …

Ovarian epithelial carcinogenesis

J Zhang, EG Silva, AK Sood, J Liu - Gynecologic and Obstetric Pathology …, 2019 - Springer
The mortality rate of epithelial ovarian carcinoma (EOC) ranks the highest in all
gynecological malignancies, although it is the third common cancer in the female …

[HTML][HTML] 基于磷酸化修饰组学分析WNK2 调控卵巢癌细胞骨架形成

李凤杰, 贾永琴, 梁振, 胡彬, 贺思敏, 王延洲, 杨泽宇… - 2022 - aammt.tmmu.edu.cn
目的通过蛋白质磷酸化修饰组学质谱测序, 分析蛋白激酶WNK2 在卵巢癌细胞中调控的生物过程
. 方法用WNK2 干扰慢病毒感染SKOV3 细胞系, 药筛获得稳转细胞株, 提取总蛋白进行蛋白质 …

Discovery of metabolomic biomarkers for discriminating platinum-sensitive and platinum-resistant ovarian cancer by using GC-MS

EC Eroglu, S Tunug, OF Geckil… - … Journal of Mass …, 2021 - journals.sagepub.com
This study aims to determine ovarian cancer (OC) patients with platinum resistance for
alternative treatment protocols by using metabolomic methodologies. Urine and serum …