Simple Summary The hnRNP A/B family of proteins (comprised of A1, A2/B1, A3, and A0)
contributes to the regulation of the majority of cellular RNAs. Here, we provide a …

Cancer remains the second leading cause of death, accounting for approximately 20% of all
fatalities. Evolving cancer cells and a dysregulated immune system create complex tumor …

Telomeres are DNA structures that protect chromosome ends. However, telomeres shorten
during cell replication and at critically low lengths can reduce cell replicative potential …

Mitochondria change their shape through fusion and fission in order to adapt to their
metabolic milieu. Mitofusin-2 (MFN2) is a key regulatory protein in this process, mediating …

Dyskeratosis congenita (DC) is a rare genetic disorder characterized by deficiencies in
telomere maintenance leading to very short telomeres and the premature onset of certain …

We define and discuss several proposed biological aging markers that have been examined
in SMDs, we review the most recent findings, and we conclude with opinions regarding the …

Acetylation is one of the key post-translational protein modifications catalysed by the protein
lysine acetyltransferases (KATs). KATs catalyse the transfer of acetyl groups to the epsilon …

Aging is an important and inevitable biological process in human life, associated with the
onset of chronic disease and death. The mechanisms behind aging remain unclear …

Cardiovascular disease (CVD) remains the leading cause of morbility and mortality
worldwide. The identification of common cardiovascular risk factors has led to the …

Accumulated alterations in metabolic control provide energy and anabolic demands for
enhanced cancer cell proliferation. Exemplified by the Warburg effect, changes in glucose …