Metabolic Regulation of Immune Responses to Mycobacterium tuberculosis: A Spotlight on L-Arginine and L-Tryptophan Metabolism

RR Crowther, JE Qualls - Frontiers in immunology, 2021 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a leading
cause of death worldwide. Despite decades of research, there is still much to be uncovered …

Genetic, Immunological, and Clinical Features of 830 Patients with Mendelian Susceptibility to Mycobacterial Diseases (MSMD): A Systematic Review

A Khavandegar, SA Mahdaviani, M Zaki-Dizaji… - Journal of Allergy and …, 2024 - Elsevier
Background Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare clinical
syndrome characterized by vulnerability to weakly virulent mycobacterial species, including …

Immune correlates of disseminated BCG infection in IL12RB1-deficient mice

X Wang, L Jia, Y Liu, J Wang, C Qiu, T Li, W Zhang… - Vaccines, 2022 - mdpi.com
Interleukin-12 receptor β1 (IL12RB1)-deficient individuals show increased susceptibilities to
local or disseminated BCG infection and environmental mycobacteria infection. However …

[PDF][PDF] Biological and clinical significance of T helper 17 cell deficiency: insight into monogenic defects

AU Anka, IN Abdullahi, K Umar, ZM Bello… - Eur Ann Allergy Clin …, 2021 - academia.edu
Abstract T helper 17 (Th17) are a CD4+ T subpopulation cells which are involved in the host
protection against microbes such as extracellular and intracellular bacteria, parasites, fungi …

Immune system profile of newborns born to mothers treated with TNF inhibitors through pregnancy

Y Luo - 2024 - diposit.ub.edu
[eng] This thesis is framed in the concept that tumor necrosis factor (TNF) is a fundamental
cytokine for: 1) the immune responses against mycobacterial challenge being a key …

Disseminated Salmonellosis and cutaneous vasculitis in a child with IL12Rß1 deficiency–a case report & review of literature.

RS Mohite, KG Rajeshwari, MN Vidya, S Bhattad - Authorea Preprints, 2024 - techrxiv.org
Mendelian susceptibility to mycobacterial disease (MSMD) is a group of genetic disorders
characterized by a defect in interferon γ (IFN γ)–mediated immunity, with predisposition to …

Evaluation of the sixth coding exon of IL12RB1 in patients afflicted by the non-healing form of cutaneous Leishmaniasis

M Moafi, H Rezvan, R Taleban, M Mansourian… - 2025 - researchsquare.com
Abstract Background and Objective: Cutaneous Leishmaniasis (CL) appears as a localized
skin lesion, that is curable without any clinical intervention. However, Leishmania infection …

[PDF][PDF] Disseminated Salmonellosis in a child with IL12Rß1 deficiency–Case report and review of literature.

RS Mohite, RK Gangulappa, VM Narasimhamurthy… - 2021 - assets-eu.researchsquare.com
Mendelian susceptibility to mycobacterial disease (MSMD) is a group of genetic disorders
characterized by a defect in interferon γ (IFN γ)–mediated immunity, with predisposition to …